Protein Alignment lqf and epn3

DIOPT Version :10

• Sequence 1: NP_729266.2
• Gene: lqf / 38846
• FlyBaseID: FBgn0028582
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_001005693.1
• Gene: epn3 / 448199
• XenbaseID: XB-GENE-946745
• Length: 603
• Species: Xenopus tropicalis
• Alignment Length: 746
• Identity: 240/746 - (32%)
• Similarity: 349/746 - (46%)
• Gaps: 225/746 - (30%)

  Fly    13 AGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDHG 77
            :.:||.:||:.||||:|:|||||||||||||||.::||||:.:|::..||.|:|.||||||||.|
 Frog     4 SSIRRQVKNIVHNYSEAEVKVREATSNDPWGPSTSLMSEISLMTHHAEAFPEVMIMIWKRLNDSG 68

  Fly    78 KNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFE-EGKDQGTHVREKAKQLVTL 141
            ||||||||||.||:||||.||:||.::|.|||.::|||::|.:.: :|||||.:|||||||:|:|
 Frog    69 KNWRHVYKALTLLDYLIKNGSKKVVEECNENIHSVQTLKDFQFLDRDGKDQGINVREKAKQIVSL 133

  Fly   142 LKDDERLKNERVKAQKAKER--------------FAQNPSGFGSDGYIDGPSQRDLPPGWQEEPP 192
            |||:||||.||::|:..:.|              |:|..||..|          ||.|
 Frog   134 LKDEERLKQERIQAKNTRRRISQGVNAISTRKISFSQAASGTCS----------DLSP------- 181

  Fly   193 KSVSELEMVRPQTAGEEELQLQLAMAMSREEAEQEE---AKRRSDDVRLQLALSQSEQDFK---- 250
                :||..|||::||||||||||:||||||||:::   |....::.::|.||:||:::::
 Frog   182 ----DLEQARPQSSGEEELQLQLALAMSREEAEKKKVPSAPDEEEEQQIQAALNQSKEEYEKQIR 242

  Fly   251 ----------------DPNG--RPIPAPKK-EEQQSHLLDLLDISLGATSISSPPLGAAGGAPTA 296
                            .|:.  ..:.|.:| |:.::|||||:|:.
 Frog   243 LAQGEKSLLEKALNQFQPSSEYHELEAVRKPEKSETHLLDLVDVF-------------------- 287

  Fly   297 VVDPWAMPGPRAPSQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQS 361
                    || |||..:|||:..|  .:.|.|.            |..||..|:....| |.|.:
 Frog   288 --------GP-APSASTDPWNSVS--LLTPNNG------------PTRSASFGSLYPTW-ATTAN 328

  Fly   362 PSVASGSSNEGW----LQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSS 422
            .:.|:|||:..|    |.:....:|..:... .|..:...|.|.|.|
 Frog   329 GASATGSSSLPWDTPSLSTQLREDQTSQSII-FGSESSAGLKKPTIV------------------ 374

  Fly   423 SDPWLAEPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSP-EFDEFDLIT 486
                :..||            :|||.....|..|     :.:|:    :...:|| |.|.|..:.
 Frog   375 ----VKSPA------------SDPWGDSLPSPDG-----NTFKS----SSMPESPFELDLFGEVV 414

  Fly   487 NRNKSEHSNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGENSAL 551
            :..|     ||..:.:..:|.|.:|...||             |.....:|..|..:     .:|
 Frog   415 STTK-----SNPDSLDLKALEDSLDDDKAN-------------TRCRTPESFLDPAA-----RSL 456

  Fly   552 VNLDNLIKPIAPQTQTGNQPAYNPFSDNVVPPKTNLFQQQQPAVPSINQLKQQAPFSVSMNQDPW 616
            ||||:|| |.|..:....    |||:.....|..|...|......|:||::..:|       :|.
 Frog   457 VNLDSLI-PGAGFSAKNR----NPFASGRNAPAPNNLSQLGEQKLSLNQMRTTSP-------EPG 509

  Fly   617 --APVMGGVSTTSQPKL---PPP------------VRPTSLNL------GPSSVGEFQLLSALSN 658
              ||::...:.::.|.:   |.|            |.|||..|      .|:::|   :..:||.
 Frog   510 AAAPLIPVQNVSTMPAISMGPIPNTLPAFSTGPGFVMPTSNQLLMPLYGHPAALG---IPPSLSV 571

  Fly   659 PI--IPIAH-----IPQP-QPNL-QVYNNAY 680
            |:  :|..|     :|.| ||.. |..||.:
 Frog   572 PLHQVPALHQVPITLPPPIQPQFSQGGNNPF 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lqf	NP_729266.2	ENTH_Epsin	28..150	CDD:340787	82/122 (67%)
		UIM	208..227	CDD:197845	17/18 (94%)
		PHA03247	<278..394	CDD:223021	26/119 (22%)
epn3	NP_001005693.1	ENTH_Epsin	19..142	CDD:340787	82/122 (67%)
		mukB	<93..>268	CDD:235316	71/195 (36%)
		PHA03247	<287..593	CDD:223021	94/431 (22%)
		PAT1	<482..>601	CDD:401645	31/128 (24%)