Protein Alignment lqf and Enthd1

DIOPT Version :10

• Sequence 1: NP_729266.2
• Gene: lqf / 38846
• FlyBaseID: FBgn0028582
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_001156661.1
• Gene: Enthd1 / 383075
• MGIID: 2686088
• Length: 618
• Species: Mus musculus
• Alignment Length: 702
• Identity: 184/702 - (26%)
• Similarity: 288/702 - (41%)
• Gaps: 193/702 - (27%)

  Fly    16 RRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDHGKNW 80
            ||.:||...|||||:.||||||||||||||:::|..|:::|:|..:.||||.|:|:||:||||||
Mouse     4 RRQVKNFVKNYSDAEKKVREATSNDPWGPSSSLMLAISDMTFNAASLSEIMHMLWQRLSDHGKNW 68

  Fly    81 RHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFEE-GKDQGTHVREKAKQLVTLLKD 144
            |||||:|.|::||||.||.||.|.|:|.:..:|.|::|.:.:| |||||.::||::||::|||.|
Mouse    69 RHVYKSLALMDYLIKNGSRKVIQYCREGVCNLQMLKDFQHIDEAGKDQGHYIRERSKQVITLLMD 133

  Fly   145 DERLKNERVKAQKAKERFAQN---PSGFGSDGYIDGPSQRDLPPGWQEEPPKSVSELEMVRPQTA 206
            ::.|..||..|...::|.:.:   ||...:.|               ..|....|.|
Mouse   134 EQLLHKEREVATWTRQRTSYSMSFPSRLSATG---------------TSPTVCTSVL-------- 175

  Fly   207 GEEELQLQLAMAMSREEAEQEEAKR------RSDDVRLQLALSQSEQDFKDPNGRPIPAPKKEEQ 265
                    :..:::.|:...::.|:      :.:..:.:|.|.|. ||...|.|..:|
Mouse   176 --------IPESLTSEKKHSQDCKKTAGLCSKKNTSKARLRLEQC-QDVPSPAGTSLP------- 224

  Fly   266 QSHLLDLLDISLGATSISSP-----------PLGAAGGAPTAVVDP--WAMPGPRAPSQLSDPWS 317
                  |...|||..:..|.           |.......|.:...|  |...|......|.|..:
Mouse   225 ------LYFPSLGMKAWKSTEDLTLLYSYEHPKQPVTRLPPSFTSPASWLSEGEAEICNLWDTEA 283

  Fly   318 GTSSPQVDPWNPSAAPRTILGAGVPMTSA---------------------------PLGA----G 351
            .::.|:.:|     :.:|.:..|..:.||                           ||.|    |
Mouse   284 VSTPPEKNP-----SMQTSVSLGKKLESAIANTITESPPQTPQEKQMAAKSFEMPTPLPAFWPSG 343

  Fly   352 NDAWGA----RTQSPSVASGSSNEGWL------QSNGNANQNGRG-ATPA------------GPP 393
            .|.:.:    .::|.|:....|:...|      ::....|:..:. .|||            .|.
Mouse   344 KDEFVSLALRMSKSESIFHTQSSVETLYVSPTFKTISPLNETSQDLQTPAQFSICQMEDVCLKPL 408

  Fly   394 A-EGWLIKSTAVGALGAAPINHAANNGSSSSDPWLAEPAASAAGGAAAVGLADPWAPGAASQTGA 457
            | .|......|..|:.||....::.:..|.|.|.||.|..||......:..:..|
Mouse   409 AMRGEWTPKQASEAVSAASEVASSFSTLSISPPDLAHPEKSARCFIPVMASSSFW---------- 463

  Fly   458 GALDDPWKALGTGAIKKQSPEFDEFDLITNRNKS---EH-----SNSNASNNNNASLLDDMDPLS 514
             .|..|           |||.    |.:|::|::   .|     |.:::.|....||.|:.|
Mouse   464 -TLPQP-----------QSPS----DPLTDQNEAVRVRHPFAPTSTASSDNEEYPSLPDNSD--- 509

  Fly   515 ANYGNGGINSSMHP----STGATAKKSIKDAH-------SFLGENSALVNLDNLIKPIAPQTQTG 568
                    ::...|    |:|..|..::..||       ||..:.||.::.|:..:.|.  |..|
Mouse   510 --------STMKEPSYSFSSGRGAFSTLTRAHFPGLPQASFRFQESAGLSRDSESRAIC--TLLG 564

  Fly   569 N-QPAYNPFSDNVVPPKTNLFQQQQPAVPS-INQLKQQAPFSVSMNQDPWAP 618
            . :.|.....|::     :|..|:...:.| :..|...:|......|||.:|
Mouse   565 EVKSAVVRLHDDL-----SLVIQELSVINSRLGNLSGSSPTVSETLQDPQSP 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lqf	NP_729266.2	ENTH_Epsin	28..150	CDD:340787	70/122 (57%)
		UIM	208..227	CDD:197845	1/18 (6%)
		PHA03247	<278..394	CDD:223021	29/182 (16%)
Enthd1	NP_001156661.1	ENTH_Epsin	16..139	CDD:340787	70/122 (57%)