Protein Alignment lqf and Epn3

DIOPT Version :9

• Sequence 1: NP_729266.2
• Gene: lqf / 38846
• FlyBaseID: FBgn0028582
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: XP_006247263.1
• Gene: Epn3 / 360605
• RGDID: 1306416
• Length: 635
• Species: Rattus norvegicus
• Alignment Length: 712
• Identity: 270/712 - (37%)
• Similarity: 371/712 - (52%)
• Gaps: 150/712 - (21%)

  Fly    10 VNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLN 74
            :..:.|||.:||:.||||:|::|||||||||||||.:::|||||:||:|.|||:|:|.|:|:|||
  Rat     1 MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMVWRRLN 65

  Fly    75 DHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFE-EGKDQGTHVREKAKQL 138
            |.|||||||||||.||:||:|||||:||.||:||::.||||::|.|.: :|||||.:||||.||:
  Rat    66 DSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQV 130

  Fly   139 VTLLKDDERLKNERVKAQKAKERFAQNPSGFGSDGYIDGPSQRDLPPGW--QEEPPKSVSELEMV 201
            :.||||:|||:.||..|.|.|||.|....|.||.........|..|..:  ....|:..|:||..
  Rat   131 MALLKDEERLRQERTHALKTKERMALEGMGIGSGQLGFSRRSRGSPSSYTSASSSPRYASDLEQA 195

  Fly   202 RPQTAGEEELQLQLAMAMSREEAEQ--EEAKRRSDDVRLQLALSQSEQ------------DFKDP 252
            ||||:||||||||||:||||||||:  ..|..|.:|::||||||.|.|            ||...
  Rat   196 RPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQLQLALSLSRQEHEKGGRSWKGDDFPVA 260

  Fly   253 NGRPIPA--------PKKEEQ---------QSHLLDLLDISLGATSISSPPLGAAGGAPTAVVDP 300
            ||.. ||        |::||:         ||.:|||.|:...|.::.|....|         ||
  Rat   261 NGAE-PAGQRRRDREPEREERKEEEKLKTSQSSILDLADVFAPAPALPSTHCSA---------DP 315

  Fly   301 WAMPGPRAPSQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQS---- 361
            |.:||.| |:  ::|...:..|..|||:|           ||       :||..  :|:|.
  Rat   316 WDIPGLR-PN--TEPSGSSWGPSADPWSP-----------VP-------SGNAL--SRSQPWDLL 357

  Fly   362 PSVASGSSNEGWLQSNGNANQNGR-GATPAGPP-AEGWLIKSTAVGALGAAPINHAANNGSSSSD 424
            |::   ||:|.|          || ...|:||| .:.|            ||.:......|:..|
  Rat   358 PTL---SSSEPW----------GRTPVLPSGPPITDPW------------APSSPTPKLPSTGVD 397

  Fly   425 PWLAEPAASAAGGAAAVGLADPWAPGAASQTGAGALD--DPWKALGTGAIKKQSP-EFDEFDLIT 486
            ||.|....|   ..:|:|.|.|:.|.|........::  |..:||..|  |..|| |.|.|.
  Rat   398 PWGASVETS---NTSALGGASPFDPFAKPLESTEPMESRDSAQALPKG--KSPSPVELDPFG--- 454

  Fly   487 NRNKSEHSNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGEN-SA 550
                   .:|.:...|.....:.:|       .|.:..::....|..| :..:...||||.: |:
  Rat   455 -------DSSPSCKQNGVKETEALD-------LGVLGEALTQQPGKEA-RPCRTPESFLGPSASS 504

  Fly   551 LVNLDNLIK-PIAPQTQTGNQPAYNPFSDNV-VPPKTNLFQQQQPAVPSINQLKQQAPFSVSMNQ 613
            |||||:|:| |:|.:|:       |||...: .|..||.|...:...|::||::..:|   ::..
  Rat   505 LVNLDSLVKAPLAARTR-------NPFLTGLSAPSPTNPFGAGEQGRPTLNQMRTGSP---ALGL 559

  Fly   614 DPWAPVMGGV---STTSQPKLPPPVRPTSLNLG---PSSVGEFQLLSALSNPIIPIAHIPQP 669
            .|..||  ||   |.|....||.|:  :|:.:|   |:||..|....|.:.|  | |.:|||
  Rat   560 PPGGPV--GVPLGSMTYSASLPLPL--SSVPVGATLPASVSVFPQAGAFAPP--P-ASLPQP 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lqf	NP_729266.2	ENTH_epsin	28..149	CDD:239627	82/121 (68%)
		UIM	208..227	CDD:197845	17/20 (85%)
Epn3	XP_006247263.1	ENTH_epsin	19..141	CDD:239627	82/121 (68%)
		UIM	202..221	CDD:197845	17/18 (94%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337636
Domainoid	1	1.000	208	1.000	Domainoid score	I2758
eggNOG	1	0.900	-	-		E1_KOG2056
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	367	1.000	Inparanoid score	I2084
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263849at2759
OrthoFinder	1	1.000	-	-		FOG0000780
OrthoInspector	1	1.000	-	-		otm45941
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12276
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X540
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.900