Protein Alignment lqf and Epn2

DIOPT Version :10

• Sequence 1: NP_729266.2
• Gene: lqf / 38846
• FlyBaseID: FBgn0028582
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_001349514.1
• Gene: Epn2 / 13855
• MGIID: 1333766
• Length: 652
• Species: Mus musculus
• Alignment Length: 804
• Identity: 285/804 - (35%)
• Similarity: 365/804 - (45%)
• Gaps: 282/804 - (35%)

  Fly    10 VNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLN 74
            :..:.:||.:||:.:|||:|::||||||||||||||:::|:|||:||||||||||||.|:|||||
Mouse     1 MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLN 65

  Fly    75 DHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFE-EGKDQGTHVREKAKQL 138
            |||||||||||||.||:||||||||:|||||:|||||||||::|.|.: :|||||.:||||:|||
Mouse    66 DHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQL 130

  Fly   139 VTLLKDDERLKNERVKAQKAKERFAQNPSGFGSD------------------------------- 172
            |.||||:||||.|||:|.|.|||.||..:|.||:
Mouse   131 VALLKDEERLKVERVQALKTKERMAQVATGVGSNQITFGRGSSQPNLSTSYSEQEYGKAGGSPAS 195

  Fly   173 ---------------GYIDGPSQRDLPPGWQEEP------------------------------P 192
                           |.:.|.|: :|.|..|..|                              |
Mouse   196 YHGSPEASLCPQHRTGAMLGQSE-ELQPLSQRHPCLPHLGLASHPNGDWAQPCLTCDRAARATSP 259

  Fly   193 KSVSELEMVRPQTAGEEELQLQLAMAMSREEAEQ------------EEAKRRSDDVRLQLALSQS 245
            :..||||..||||:||||||||||:|||||.|||            ||..||.||:|||:||.:|
Mouse   260 RVSSELEQARPQTSGEEELQLQLALAMSREVAEQSSESVQTARGSKEERLRRGDDLRLQMALEES 324

  Fly   246 EQDFKDPNGRPIPAPKKEE-----------QQSHLLDLLDI--SLGATSISSPPLGAAGGAPTAV 297
            .:|       .:..|||:|           ||:.||||:|.  |.|..:..:.|..|  ||....
Mouse   325 RRD-------TVKVPKKKEAKACCKPGSHSQQTTLLDLMDALPSSGPVTQKTEPWSA--GASANQ 380

  Fly   298 VDPWAMPGPRAPSQLSDPWS--GTS-SPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGART 359
            .:||.  |..|||.::|||.  ||. :..||||            |||.|            |.|
Mouse   381 TNPWG--GTVAPSNITDPWPSFGTKPAASVDPW------------GVPTT------------AST 419

  Fly   360 QSPSVASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSD 424
            ||                                                .|.|         ||
Mouse   420 QS------------------------------------------------VPKN---------SD 427

  Fly   425 PWLA--EPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITN 487
            ||.|  :||::|.....|.|.|.|     :|.:|:..|...:    .|.:|   .:|.|||.:..
Mouse   428 PWAASQQPASNAGKTTDAWGAAKP-----SSASGSFELFSNF----NGTVK---DDFSEFDNLRT 480

  Fly   488 RNKSEHSNSNA----SNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGEN 548
            ..|...|.::.    |...:..|.:.....||         |..||:..      |...||||.|
Mouse   481 SKKPAESGASVPPQDSRTTSPDLFESQSLTSA---------SSKPSSAR------KTPESFLGPN 530

  Fly   549 SALVNLDNLIKPIAPQTQTGNQPAYNPF--SDNVVPPKTNLFQQQQPAVPSINQLK------QQA 605
            :||||||:|:...||..|     :.|||  .....|...|.||..||...::|||:      ..|
Mouse   531 AALVNLDSLVTKPAPPAQ-----SLNPFLAPGAAAPAPVNPFQVNQPQPLTLNQLRGSPVLGSSA 590

  Fly   606 PFSVSMNQDPWAPVMG-------GVSTTSQPKLPPPVRPTSLNLGPSSVGEFQLLSALSNPIIPI 663
            .|......:..||:..       |.|.:|.    .|:.||::|: ..|||
Mouse   591 SFGSGPGVETVAPMTSVAPHSSVGASGSSL----TPLGPTAMNM-VGSVG--------------- 635

  Fly   664 AHIPQPQPNLQVYNNAYQSSSSTN 687
              ||.         :|.||:.:||
Mouse   636 --IPP---------SAAQSTGTTN 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lqf	NP_729266.2	ENTH_Epsin	28..150	CDD:340787	96/122 (79%)
		UIM	208..227	CDD:197845	17/30 (57%)
		PHA03247	<278..394	CDD:223021	28/118 (24%)
Epn2	NP_001349514.1	ENTH_Epsin	19..141	CDD:340787	95/121 (79%)