Protein Alignment lqf and Epn1

DIOPT Version :9

• Sequence 1: NP_729266.2
• Gene: lqf / 38846
• FlyBaseID: FBgn0028582
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: XP_036008550.1
• Gene: Epn1 / 13854
• MGIID: 1333763
• Length: 654
• Species: Mus musculus
• Alignment Length: 678
• Identity: 266/678 - (39%)
• Similarity: 346/678 - (51%)
• Gaps: 149/678 - (21%)

  Fly    10 VNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLN 74
            ::.:.|||.:||:.||||:|::||||||||||||||:::|||||:||||||||||||.|||||||
Mouse    80 MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLN 144

  Fly    75 DHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFE-EGKDQGTHVREKAKQL 138
            ||||||||||||:.|:|||||||||:|:||||||::|:|||::|.|.: :|||||.:||||||||
Mouse   145 DHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQL 209

  Fly   139 VTLLKDDERLKNERVKAQKAKERFAQNPSGFGSDGYIDGPSQRDLPPGWQEEPPKSVSELEMVRP 203
            |.||:|::||:.||..|.|.||:.||..:. .|.....||            ||    |.|...|
Mouse   210 VALLRDEDRLREERAHALKTKEKLAQTATA-SSAAVGSGP------------PP----EAEQAWP 257

  Fly   204 QTAGEEELQLQLAMAMSREEAEQEEAKRRSDDVRLQLALSQS-EQDFKDPNGR---------PIP 258
            |::||||||||||:|||:|||:|..:....|||:||||||.| |:..|:...|         .|.
Mouse   258 QSSGEEELQLQLALAMSKEEADQPPSCGPEDDVQLQLALSLSREEHDKEERIRRGDDLRLQMAIE 322

  Fly   259 APKKE---EQQSHLLDLLDI-SLGATSISSPPLGAAGGAPTAV------VDPWAMPGPRAPSQLS 313
            ..|:|   :::|.|:||.|: :..|...:|.|.|.....||||      .|||.  ||..| ..:
Mouse   323 ESKRETGGKEESSLMDLADVFTTPAPPQASDPWGGPASVPTAVPVAAAASDPWG--GPAVP-PAA 384

  Fly   314 DPWSGTSSPQV--DPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPSVASGSSNEGWLQS 376
            |||.|.:....  |||.|               :||.|...|.||. |.:|:...|.:.:.|..|
Mouse   385 DPWGGAAPTPASGDPWRP---------------AAPTGPSVDPWGG-TPAPAAGEGPTPDPWGSS 433

  Fly   377 NGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLAEPAASAAGGAAAV 441
            :|       ||..:|||                            |||||...||.|
Mouse   434 DG-------GAPVSGPP----------------------------SSDPWAPAPAFS-------- 455

  Fly   442 GLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITNRNKSEHSNSNASNNNNASL 506
               |||....|..:..|.        ..|....:..||.:||    |.::....|.:|......|
Mouse   456 ---DPWGGSPAKPSSNGT--------AVGGFDTEPDEFSDFD----RLRTALPTSGSSTGELELL 505

  Fly   507 LDDMDPLSAN-YGNGGINSSMHPSTGATAKKSI--------KDAHSFLGENSALVNLDNLIKPIA 562
            ..::...|.. :...|:..|:..|.|:....:.        |...||||.|:|||:||:|:....
Mouse   506 AGEVPARSPGAFDMSGVGGSLAESVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPG 570

  Fly   563 PQTQTGNQPAYNPFSDNVVPPK----TNLFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVMGGV 623
            | |..|:: |.|||..:..||.    ||.||...||..::|||:          ..|..||.|..
Mouse   571 P-TPPGSK-ASNPFLPSGAPPTGPSVTNPFQPAPPATLTLNQLR----------LSPVPPVPGAP 623

  Fly   624 ST-----TSQPKLPP--PVRPTSLNLGP 644
            .|     ...|.|||  |..|.:.|..|
Mouse   624 PTYISPLGGGPGLPPMMPPGPPAPNTNP 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lqf	NP_729266.2	ENTH_epsin	28..149	CDD:239627	92/121 (76%)
		UIM	208..227	CDD:197845	15/18 (83%)
Epn1	XP_036008550.1	ENTH_Epsin	98..221	CDD:340787	93/122 (76%)
		PRK07764	<349..516	CDD:236090	61/243 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834093
Domainoid	1	1.000	210	1.000	Domainoid score	I2811
eggNOG	1	0.900	-	-		E1_KOG2056
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32172
Inparanoid	1	1.050	369	1.000	Inparanoid score	I2121
Isobase	1	0.950	-	0	Normalized mean entropy	S1984
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000780
OrthoInspector	1	1.000	-	-		otm43853
orthoMCL	1	0.900	-	-		OOG6_103058
Panther	1	1.100	-	-	O	PTHR12276
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2102
SonicParanoid	1	1.000	-	-		X540
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.730