Protein Alignment ltl and CG5810

DIOPT Version :9

• Sequence 1: NP_001261524.1
• Gene: ltl / 38845
• FlyBaseID: FBgn0268063
• Length: 817
• Species: Drosophila melanogaster
• Sequence 2: NP_650952.2
• Gene: CG5810 / 42513
• FlyBaseID: FBgn0038866
• Length: 428
• Species: Drosophila melanogaster
• Alignment Length: 477
• Identity: 106/477 - (22%)
• Similarity: 192/477 - (40%)
• Gaps: 115/477 - (24%)

  Fly    22 ISPCTCETGKAWNHVELSCEKLESFNAVVDSLANKLNADTNIDLKITHSQLDDLEMRSFTDMNFN 86
            |:..|||:           :|||..  .:|||..:.|..||  ||...:
  Fly    15 IAFATCES-----------QKLEEI--AIDSLDCRENTCTN--LKYPSA---------------- 48

  Fly    87 LYKLRMQWNSLKSLPEVPFRGLSNVTYLSIGDNDLDEIPKHALSHMPSLLTLDIGRCKIRAVQQE 151
                    :::....|...:.|.....|.:..:||..:|:....::|.|:...:..|:::.::..
  Fly    49 --------SAVAYFSENVTKHLRKYETLVLHSSDLANLPRKIFLNLPQLVEFHVLECELQQIESV 105

  Fly   152 DFRGIQRVTNLILVSNIITRLDRGSFPKSLLI--LHLGRNQLESLNGSL-HDLHNLESLFINANN 213
            .|.|.:.:..|....|.:..||..:|..:..:  |:|..||||.|..:: ..|.||:.:.::.|.
  Fly   106 CFDGAKNLKRLNFGGNALRVLDSNTFELATQLEELNLSDNQLEDLPTTIFRPLKNLQKINLSNNR 170

  Fly   214 ITSLDDEL-PDGGQLRLLMAHNNRLERLPANMAGMHSLETVHIHCNQLRSFDRVLRNAVNLSEVM 277
            :.:|...: ...|.|:.:...:|:|..||..:.                   |..|.  :|||..
  Fly   171 LITLSQHIFSQLGSLKSINVDSNQLVELPGELF-------------------RDQRK--HLSEFS 214

  Fly   278 ADNNELEYLAQDEFASCSKVETLQMGCNHIKSLNSSLLPILKLKNANFSFNDIE----EFSMAEL 338
            |.:|:|..:..:.|             ..|..|:.|..|.|:..:.:...|::|    :....||
  Fly   215 AQSNQLVRIPFNIF-------------REIDHLSLSFNPQLRRLHLSAKINELEATNCDLESVEL 266

  Fly   339 HGLRSLKTLQLSSN-RIQRL-LPDPRGVQELMLVNLDLDNNRIDSLNGA--LAGLGNLRILNLAG 399
            .|  .:..:||.:| ::..| :..|:.::.|.|.|.:|  .|:|.|:.|  |..|....|:|||
  Fly   267 DG--RVIGVQLEANPKLHELKISQPQDLEHLYLANTNL--YRLDFLSKASKLVDLDVTDIVNLA- 326

  Fly   400 NRLEHLQVGDFDGMIRLDIL--DLTGNQLAELKPLEMTLLPSLK---ILKVAYNN-----ITKLE 454
               :..::....|:.||...  :||.|        .|.:||.||   .|::::..     |..|:
  Fly   327 ---DLPKITSAKGLERLSFTYDNLTSN--------HMDMLPHLKDLNYLEISHEKGKEIFIKDLD 380

  Fly   455 QDFKGLPVLCQANLTNNQISTI 476
            :||    .:.:|.|...|::.:
  Fly   381 EDF----FVEEAELNCGQLADL 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ltl	NP_001261524.1	leucine-rich repeat	65..86	CDD:275380	2/20 (10%)
		LRR_8	86..145	CDD:290566	9/58 (16%)
		leucine-rich repeat	87..110	CDD:275380	2/22 (9%)
		leucine-rich repeat	111..134	CDD:275380	4/22 (18%)
		leucine-rich repeat	135..158	CDD:275380	4/22 (18%)
		LRR_8	158..214	CDD:290566	16/58 (28%)
		leucine-rich repeat	159..180	CDD:275380	5/20 (25%)
		leucine-rich repeat	181..203	CDD:275380	8/24 (33%)
		leucine-rich repeat	204..226	CDD:275380	3/22 (14%)
		LRR_RI	226..451	CDD:238064	55/242 (23%)
		leucine-rich repeat	227..249	CDD:275380	5/21 (24%)
		leucine-rich repeat	250..272	CDD:275380	2/21 (10%)
		leucine-rich repeat	273..296	CDD:275380	7/22 (32%)
		leucine-rich repeat	297..315	CDD:275380	3/17 (18%)
		LRR_8	319..402	CDD:290566	24/90 (27%)
		leucine-rich repeat	320..335	CDD:275378	2/18 (11%)
		leucine-rich repeat	344..366	CDD:275380	5/23 (22%)
		leucine-rich repeat	367..391	CDD:275380	10/25 (40%)
		LRR_8	369..426	CDD:290566	19/60 (32%)
		leucine-rich repeat	392..415	CDD:275380	5/22 (23%)
		leucine-rich repeat	416..439	CDD:275380	6/24 (25%)
		LRR_8	438..>479	CDD:290566	11/47 (23%)
		leucine-rich repeat	440..462	CDD:275380	7/29 (24%)
		leucine-rich repeat	463..483	CDD:275380	3/14 (21%)
CG5810	NP_650952.2	leucine-rich repeat	65..88	CDD:275380	4/22 (18%)
		LRR_8	87..147	CDD:290566	13/59 (22%)
		leucine-rich repeat	89..112	CDD:275380	4/22 (18%)
		leucine-rich repeat	113..136	CDD:275380	5/22 (23%)
		LRR_8	135..195	CDD:290566	15/59 (25%)
		LRR_4	135..175	CDD:289563	11/39 (28%)
		leucine-rich repeat	137..160	CDD:275380	8/22 (36%)
		leucine-rich repeat	161..184	CDD:275380	3/22 (14%)
		leucine-rich repeat	185..209	CDD:275380	7/44 (16%)
		leucine-rich repeat	210..231	CDD:275380	7/33 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453652
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930