Protein Alignment ltl and trn

DIOPT Version :10

• Sequence 1: NP_729265.1
• Gene: ltl / 38845
• FlyBaseID: FBgn0268063
• Length: 817
• Species: Drosophila melanogaster
• Sequence 2: NP_001261796.1
• Gene: trn / 39491
• FlyBaseID: FBgn0010452
• Length: 751
• Species: Drosophila melanogaster
• Alignment Length: 848
• Identity: 179/848 - (21%)
• Similarity: 295/848 - (34%)
• Gaps: 246/848 - (29%)

  Fly    11 LASLQCSVRPEISPCTCETGKAWNHVELSCEKLESFNAVVDSLANKLNADTNIDLKITHSQLDDL 75
            |||:  .|.|......|..|       ..|:                  |..:.::....|||.|
  Fly    16 LASI--GVEPAAGLANCPPG-------CQCD------------------DNTLVVQCGEGQLDVL 53

  Fly    76 EMRSFTDMNFNLYKLRMQWNSLKSLPEVPFRGLSNVTYLSIGDNDLDEIPKHALSHMPSLLTLDI 140
            .:.    :|.::.:|.::.|.:|:: :...:..:.:|:|.:..|.|..||:...::...|..:.:
  Fly    54 PIA----LNPSIQRLVIKSNKIKTI-DSSIQFYAELTFLDLSSNHLMTIPQRTFAYQKKLQEVHL 113

  Fly   141 GRCKIRAVQQEDFRGIQRVTNLILVSNIITRLDRGSFPKSLLILHLGRNQLESLNGSLHDLHNLE 205
            ...||..:..:.|.|:..||.|.|..|.|:.|.:|:|...|        ::|.||
  Fly   114 NHNKIGQISNKTFIGLSAVTVLNLRGNQISELHQGTFTPLL--------KIEELN---------- 160

  Fly   206 SLFINANNITSLDDELPDG-GQLRLLMAHNNRLERLPANMAGMHSLETVHIHCNQLRSFDRVLRN 269
               :..|.|..||.:..|| .|||:|...:|.|..:|                      |.|:..
  Fly   161 ---LGENRIGYLDPKAFDGLSQLRILYLDDNALTTVP----------------------DPVIFQ 200

  Fly   270 AV-NLSEVMADNNELEYLAQDEFASCSKVETLQMGCNHIKSLNSSLLPILKLKNANFSFNDIEEF 333
            |: :|:|:....|.|:.:..|.|             ..:|.|..     |:||.|:     :...
  Fly   201 AMPSLAELFLGMNTLQSIQADAF-------------QDLKGLTR-----LELKGAS-----LRNI 242

  Fly   334 SMAELHGLRSLKTLQLSSNRIQRLLPDPR-GVQELM-LVNLDLDNNRIDSLN-GALAGLGNLRIL 395
            |.....||:.|:.|.||.||:.|:   |. |:.:|: |..|.|..|..:.:: ||..||..|:.|
  Fly   243 SHDSFLGLQELRILDLSDNRLDRI---PSVGLSKLVRLEQLSLGQNDFEVISEGAFMGLKQLKRL 304

  Fly   396 NLAGN-RLEHLQVGDFDGMIRLDILDLTGNQ-LAELKPLEMTLLPSLKILKVAYNNITKLEQ--- 455
            .:.|. ||:.:..|.|.....|:.|:|:.|: |.|::...::.|..||.:.:..|.:|.|.:
  Fly   305 EVNGALRLKRVMTGAFSDNGNLEYLNLSSNKMLLEVQEGALSGLSQLKHVVLKANALTSLAEGLF 369

  Fly   456 DFKGLPVLCQANLTNNQISTISSELVTNTRCKNHNVPGKLEIHLDDNPIMCDVGLNELCRLMAVQ 520
            .:|.|..|                                  .|.:||:.||      ||:|.:.
  Fly   370 PWKDLQTL----------------------------------DLSENPLSCD------CRVMWLH 394

  Fly   521 EARIRGRSQCFENDQEVCTVLPMLYNVNLPIMVTNLKLTGREVPKPMVRVIVPSLIKANNELLPP 585
            ...:...:...:..:.:|.....|...:|..:  |..:.|.....|..:.::.:|:..:...:..
  Fly   395 NLLVAKNASQDDVSELLCEFPERLRGESLRHL--NPAMMGCTHADPRKQALIGALLVGSAATITA 457

  Fly   586 LIATL----------------GNPVL----------------------------ISTDLVNPVIS 606
            |...|                ||..|                            |.:...|...:
  Fly   458 LALVLYRCRHKIRETIKGGLWGNSALGRKEREYQKTFCDEDYMSRHQHHPCSLGIHSTFPNTYTA 522

  Fly   607 PLPPPLLLATTTPPPPLPLPVESEVEKNESTTANPVPTNYTQETTTTTSTTTTTTTTETSSQVAP 671
            |..|    ..|......|:||      |:....:  |....|:....|:|..:......:..:..
  Fly   523 PHHP----GATHHYGMCPMPV------NDLGAID--PQQKFQQLVVPTATMISEKKLNNNKALVS 575

  Fly   672 IEIITTTAPTTTTTSTTTPKPNETLPVIVELQDPN----------PPDTTVNQT----ALVPPVV 722
            ...|..:|      |......:.|:...|..|:|.          ....||..:    |.||.|.
  Fly   576 QGAIDDSA------SFVLHMKSATMGRDVHQQNPQLNHYTKPQFLSATATVGDSCYSYADVPMVH 634

  Fly   723 LDPL----QQDLEREREREREREL------ERDLDHEAVAKTEYETVEYIPNLVQPPVG-SDALT 776
            ..||    |..|...:|..::|||      ...|||..:    |....|...|.|  :| |...|
  Fly   635 GAPLGGPNQPQLRLTQEHFKQRELYDQEMGSEILDHNYI----YSNTHYSMPLEQ--LGRSKTPT 693

  Fly   777 PPP 779
            |||
  Fly   694 PPP 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ltl	NP_729265.1	LRR	65..476	CDD:443914	103/420 (25%)
		leucine-rich repeat	65..86	CDD:275380	5/20 (25%)
		leucine-rich repeat	87..110	CDD:275380	3/22 (14%)
		leucine-rich repeat	111..134	CDD:275380	6/22 (27%)
		leucine-rich repeat	135..158	CDD:275380	5/22 (23%)
		leucine-rich repeat	159..180	CDD:275380	9/20 (45%)
		leucine-rich repeat	181..203	CDD:275380	4/21 (19%)
		leucine-rich repeat	204..226	CDD:275380	6/22 (27%)
		leucine-rich repeat	227..249	CDD:275380	6/21 (29%)
		leucine-rich repeat	250..272	CDD:275380	3/22 (14%)
		leucine-rich repeat	273..296	CDD:275380	6/22 (27%)
		leucine-rich repeat	297..315	CDD:275380	2/17 (12%)
		leucine-rich repeat	320..335	CDD:275378	3/14 (21%)
		leucine-rich repeat	344..366	CDD:275380	9/22 (41%)
		leucine-rich repeat	367..391	CDD:275380	9/25 (36%)
		leucine-rich repeat	392..415	CDD:275380	7/23 (30%)
		leucine-rich repeat	416..439	CDD:275380	7/23 (30%)
		leucine-rich repeat	440..462	CDD:275380	7/24 (29%)
		leucine-rich repeat	463..483	CDD:275380	1/19 (5%)
trn	NP_001261796.1	leucine-rich repeat	62..80	CDD:275380	3/18 (17%)
		LRR	82..406	CDD:443914	103/432 (24%)
		leucine-rich repeat	84..107	CDD:275380	6/22 (27%)
		leucine-rich repeat	108..131	CDD:275380	5/22 (23%)
		leucine-rich repeat	132..155	CDD:275380	10/30 (33%)
		leucine-rich repeat	156..179	CDD:275380	9/35 (26%)
		leucine-rich repeat	180..204	CDD:275380	9/45 (20%)
		leucine-rich repeat	205..228	CDD:275380	6/35 (17%)
		leucine-rich repeat	229..252	CDD:275380	8/32 (25%)
		leucine-rich repeat	253..276	CDD:275380	10/25 (40%)
		leucine-rich repeat	277..300	CDD:275380	8/22 (36%)
		leucine-rich repeat	301..322	CDD:275380	7/20 (35%)
		leucine-rich repeat	326..350	CDD:275380	7/23 (30%)
		leucine-rich repeat	351..373	CDD:275380	5/21 (24%)
		LRRCT	382..434	CDD:214507	12/59 (20%)