Protein Alignment ltl and Lrrc24

DIOPT Version :10

• Sequence 1: NP_729265.1
• Gene: ltl / 38845
• FlyBaseID: FBgn0268063
• Length: 817
• Species: Drosophila melanogaster
• Sequence 2: NP_932787.1
• Gene: Lrrc24 / 378937
• MGIID: 3605040
• Length: 521
• Species: Mus musculus
• Alignment Length: 301
• Identity: 85/301 - (28%)
• Similarity: 130/301 - (43%)
• Gaps: 59/301 - (19%)

  Fly   346 TLQLSSNRIQRLLPD--PRGVQELMLV-------------------NLDLDNNRIDSL-NGALAG 388
            |::..:.|: |::|.  |.|.|.|.|.                   :|.|.||.:.:| :||...
Mouse    41 TVECGALRL-RVVPPGIPPGTQTLFLQDNSIAHLEQGSLAPLAALRHLYLHNNTLRALESGAFRA 104

  Fly   389 LGNLRILNLAGNRLEHLQVGDFDGMIRLDILDLTGNQLAELKPLEMTLLPSLKILKVAYNNITKL 453
            ...|..|.|.||||..|:.|.|.|:::|.:|.|.|||||:|.......||.|:.|.:..|:|..|
Mouse   105 QPRLLELALTGNRLRGLRGGAFVGLVQLRVLYLAGNQLAKLLDFTFLHLPRLQELHLQENSIELL 169

  Fly   454 E-QDFKGLPVLCQANLTNNQISTISSELVTNTRCKNHNVPGKLEI-HLDDNPIMCDVGLNELCRL 516
            | |...||..|...:|:.||:.|||.|.:...        ..|:: .|.:||..||..|:.|...
Mouse   170 EDQALAGLSSLALLDLSRNQLGTISKEALQPL--------SSLQVLRLTENPWRCDCALHWLGSW 226

  Fly   517 MAVQEARIRGRSQCFENDQEV-CTVLPMLYNVNLPIMVTNLKLTGREVPKPMVRVIVPSLIKANN 580
              ::|.   ||......|::: |...|.|...:|      |:::|..:      :.:|..:   |
Mouse   227 --IKEG---GRRLLSSRDKKITCAEPPRLALQSL------LEVSGGSL------ICIPPSV---N 271

  Fly   581 ELLPPLIATLGNPVLISTDLVNPVISPLPPPLLLATTTPPP 621
            ...|...|.||..:.::..     .|..|.||::....|.|
Mouse   272 VEPPEFTANLGEDLQVACQ-----ASGYPQPLVVWRKVPQP 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ltl	NP_729265.1	LRR	65..476	CDD:443914	51/152 (34%)
		leucine-rich repeat	65..86	CDD:275380
		leucine-rich repeat	87..110	CDD:275380
		leucine-rich repeat	111..134	CDD:275380
		leucine-rich repeat	135..158	CDD:275380
		leucine-rich repeat	159..180	CDD:275380
		leucine-rich repeat	181..203	CDD:275380
		leucine-rich repeat	204..226	CDD:275380
		leucine-rich repeat	227..249	CDD:275380
		leucine-rich repeat	250..272	CDD:275380
		leucine-rich repeat	273..296	CDD:275380
		leucine-rich repeat	297..315	CDD:275380
		leucine-rich repeat	320..335	CDD:275378
		leucine-rich repeat	344..366	CDD:275380	6/21 (29%)
		leucine-rich repeat	367..391	CDD:275380	9/43 (21%)
		leucine-rich repeat	392..415	CDD:275380	11/22 (50%)
		leucine-rich repeat	416..439	CDD:275380	10/22 (45%)
		leucine-rich repeat	440..462	CDD:275380	9/22 (41%)
		leucine-rich repeat	463..483	CDD:275380	8/19 (42%)
Lrrc24	NP_932787.1	LRR 1	59..80		4/20 (20%)
		LRR	<61..>213	CDD:443914	51/159 (32%)
		leucine-rich repeat	61..83	CDD:275380	3/21 (14%)
		LRR 2	83..104		7/20 (35%)
		LRR_8	84..142	CDD:404697	23/57 (40%)
		leucine-rich repeat	84..107	CDD:275380	7/22 (32%)
		LRR 3	107..128		10/20 (50%)
		leucine-rich repeat	108..131	CDD:275380	11/22 (50%)
		LRR 4	131..152		9/20 (45%)
		leucine-rich repeat	132..155	CDD:275380	10/22 (45%)
		LRR 5	155..176		7/20 (35%)
		leucine-rich repeat	156..179	CDD:275380	9/22 (41%)
		LRR 6	179..200		8/20 (40%)
		leucine-rich repeat	180..203	CDD:275380	8/30 (27%)
		PCC	188..>259	CDD:188093	23/89 (26%)
		Ig_3	267..357	CDD:464046	12/49 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	306..330		1/2 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	374..395