Protein Alignment ltl and Chad

DIOPT Version :10

• Sequence 1: NP_729265.1
• Gene: ltl / 38845
• FlyBaseID: FBgn0268063
• Length: 817
• Species: Drosophila melanogaster
• Sequence 2: NP_062037.1
• Gene: Chad / 29195
• RGDID: 2336
• Length: 358
• Species: Rattus norvegicus
• Alignment Length: 310
• Identity: 82/310 - (26%)
• Similarity: 131/310 - (42%)
• Gaps: 45/310 - (14%)

  Fly     1 MTSLVYTVFHLASLQCSVRPEISPCTCETGKAWNHVELSCEK--LESFNAVVDS----------- 52
            :.|||:....|.:|..      .|..|.......||  .|:|  |:....|.::
  Rat     6 LLSLVFLAILLPALAA------CPQNCHCHGDLQHV--ICDKVGLQKIPKVSETTKLLNLQRNNF 62

  Fly    53 ---LANKLNADTN-IDLKITHSQLDDLEMRSFTDMNFNLYKLRMQWNSLKSLPEVPFRGLSNVTY 113
               .||......| :.|.:.|..:.::...:|..:...:| |.:..|.::.|....|..|:.:||
  Rat    63 PVLAANSFRTVPNLVSLHLQHCNIREVAAGAFRGLKQLIY-LYLSHNDIRVLRAGAFDDLTELTY 126

  Fly   114 LSIGDNDLDEIPKHALSHMPSLLTLDIGRCKIRAVQQEDFRGIQRVTNLILVSNIITRLDRGSFP 178
            |.:..|.:.|:|:..||.:.:|..|.:...|||.::...|:|.:.:..|.|..|.:|.|..||..
  Rat   127 LYLDHNKVSELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALTSLHPGSLD 191

  Fly   179 --KSLLILHLGRNQLESL-NGSLHDLHNLESLFINANNITSLDDEL--PDGGQLRLLMAHNNRLE 238
              ::|...||.||||.|. :.:|..|..:|.|.::.|.:.|:.|..  ..|..|..|...|..||
  Rat   192 DVENLAKFHLDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLE 256

  Fly   239 RL-PANMAGMHSLETVHIHCNQLRS------FDRVLRNAVNLSEVMADNN 281
            :. .|..||:.:|:.||:..|:|..      ||       ||..:...||
  Rat   257 KFSDAAFAGVTTLKHVHLENNRLNQLPSTFPFD-------NLETLTLTNN 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ltl	NP_729265.1	LRR	65..476	CDD:443914	66/229 (29%)
		leucine-rich repeat	65..86	CDD:275380	3/20 (15%)
		leucine-rich repeat	87..110	CDD:275380	6/22 (27%)
		leucine-rich repeat	111..134	CDD:275380	8/22 (36%)
		leucine-rich repeat	135..158	CDD:275380	7/22 (32%)
		leucine-rich repeat	159..180	CDD:275380	7/22 (32%)
		leucine-rich repeat	181..203	CDD:275380	10/22 (45%)
		leucine-rich repeat	204..226	CDD:275380	6/23 (26%)
		leucine-rich repeat	227..249	CDD:275380	8/22 (36%)
		leucine-rich repeat	250..272	CDD:275380	7/27 (26%)
		leucine-rich repeat	273..296	CDD:275380	3/9 (33%)
		leucine-rich repeat	297..315	CDD:275380
		leucine-rich repeat	320..335	CDD:275378
		leucine-rich repeat	344..366	CDD:275380
		leucine-rich repeat	367..391	CDD:275380
		leucine-rich repeat	392..415	CDD:275380
		leucine-rich repeat	416..439	CDD:275380
		leucine-rich repeat	440..462	CDD:275380
		leucine-rich repeat	463..483	CDD:275380
Chad	NP_062037.1	LRRNT	22..48	CDD:396168	7/27 (26%)
		LRR	49..>300	CDD:443914	69/259 (27%)
		LRR 1	51..72		2/20 (10%)
		leucine-rich repeat	52..75	CDD:275380	2/22 (9%)
		LRR 2	75..96		4/20 (20%)
		leucine-rich repeat	76..99	CDD:275380	3/22 (14%)
		LRR 3	99..120		5/21 (24%)
		leucine-rich repeat	100..123	CDD:275380	6/23 (26%)
		LRR 4	123..144		7/20 (35%)
		leucine-rich repeat	124..147	CDD:275380	8/22 (36%)
		LRR 5	147..168		6/20 (30%)
		leucine-rich repeat	148..171	CDD:275380	7/22 (32%)
		LRR 6	171..192		7/20 (35%)
		leucine-rich repeat	172..195	CDD:275380	7/22 (32%)
		LRR 7	195..216		9/20 (45%)
		leucine-rich repeat	196..219	CDD:275380	10/22 (45%)
		LRR 8	219..240		5/20 (25%)
		leucine-rich repeat	220..243	CDD:275380	5/22 (23%)
		LRR 9	244..265		6/20 (30%)
		leucine-rich repeat	245..268	CDD:275380	8/22 (36%)
		LRR 10	268..289		5/20 (25%)
		LRRCT	299..346	CDD:214507	1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	321..358