Protein Alignment CG7546 and bag6l

DIOPT Version :10

• Sequence 1: NP_001137904.1
• Gene: CG7546 / 38844
• FlyBaseID: FBgn0035793
• Length: 1346
• Species: Drosophila melanogaster
• Sequence 2: XP_017207757.1
• Gene: bag6l / 751663
• ZFINID: ZDB-GENE-060307-2
• Length: 1192
• Species: Danio rerio
• Alignment Length: 1496
• Identity: 332/1496 - (22%)
• Similarity: 517/1496 - (34%)
• Gaps: 464/1496 - (31%)

  Fly     2 LINLKVKTLDARIHEFSIDNELTIRQFKDQIAEKTNIAAENQRIIYQGRVLVDDKQVKEYDVDGK 66
            :|.:.|||||::...|::..|.|::|||:.||....|:.:.||:||||:||.|::.:.||:||||
Zfish     6 VIEVTVKTLDSQSRTFTVRGEWTVKQFKEHIAASVEISVDKQRLIYQGKVLQDERTLTEYNVDGK 70

  Fly    67 VLHVAERPP--FSQRGANARNNDEPMRTFRNVARPPPPGMRTSPYFRALDGMLVGTMAIPVNNGP 129
            |:|:.||||  .||.|.                                            ..|.
Zfish    71 VIHLVERPPPQSSQPGG--------------------------------------------GGGG 91

  Fly   130 VAGTRPPPNRYPNSSSFCINRITVALHMIDCADNIAAYLENPAVGLNNQSLDILQRGRWSMESTV 194
            |:|:....:...:||                  ..:||..:.....||.
Zfish    92 VSGSSGAADGGSSSS------------------QSSAYTTSHDRNANNY---------------- 122

  Fly   195 VEVGVSSTDLPRNNNIID--MVQDAVTAALSHTG--ARNYTVVQLPTVYTNENGETSQQ-RTAEA 254
              |.:.:.:||  .||:|  .:|.:|...|:..|  .||..|    :..|..:|..... ...::
Zfish   123 --VMLGTFNLP--VNIMDPQQIQMSVQQMLAGVGEMGRNVRV----STSTGSSGSVDVHINVDQS 179

  Fly   255 ITSEGAAS-GAASNASGETTAATVIIEDVIETDDEVADGASDRSVTPTPEPEAEGAVGGQQVTAA 318
            :.||.... ..|.|...||.|....:|          ..:|:.|...||.|:...:........:
Zfish   180 VQSEPRMRLHLAENLLRETQALIHRLE----------GQSSEPSQQETPPPQPSSSSFSAHPMDS 234

  Fly   319 ETPTSSVGSANDAAAEGGNNSGPRRRTRPQVLAQVIQHYRGVQARLAPFVDRYYEILQNDPTFE- 382
            ..|..|| |::.:..||...|||...: |..|.:|:...|.|:.||.||::|.:.||....:.:
Zfish   235 SPPPPSV-SSSASQTEGETQSGPNHPS-PLELVEVLSEVRRVEERLRPFMERTHSILGAATSADY 297

  Fly   383 ESDTDGRENAQRIFDRVSEAFHYLSHAQHAISDLMLDLSQPGPRVL-TCRPI------LVEQSGY 440
            .::|..||..||..:.:.|:.|.|.:...|:|||..:||...||.| ..||:      ::.|||.
Zfish   298 NNNTQEREEDQRTLNLIGESLHLLGNTLVALSDLRCNLSAQPPRHLHVVRPMSHYTSPVMMQSGL 362

  Fly   441 --------IRSNNIFTPNFLAPPSGIINEPFRNRAPGSASAAGTQTATTAGTQTPTSAGTPTAVA 497
                    :.|....|.|......|....|..:........|....|..:..||....|||..:.
Zfish   363 PHIPIPMNLGSTVTMTSNSRQTSDGQPQPPHSSNQSDQQGQAPPTPANESNQQTGHGQGTPRVIR 427

  Fly   498 PSQAA---------NLQAATDASRSA-----------------------------AAMAEIASRA 524
            .:...         ||.|.:|:....                             |.|.:|:.:|
Zfish   428 ITHQTMEPVVMMQMNLDADSDSGAQGQSQQNPSAAGETGTTVPLHVPGLPPEFMQAIMHQISQQA 492

  Fly   525 AGAAAEMAAGAASAAAGAANAAAAAARDLSSDQVEDPIDEPMVGPNAAGAETLAQEQQRLEMDHD 589
            ...|...:||......|.|.|.|        ...|.|:..|              .|.|:.:
Zfish   493 VTMATAASAGHQGQQQGTAGAGA--------QNGESPVPPP--------------PQARVVI--- 532

  Fly   590 HDQAQSETPERETRPVPRLRVYVPV-----------TLPPPNPQLEMARIIQAMVNGQRPNDIHV 643
                        |||....||..|:           .:|||              :||:.|....
Zfish   533 ------------TRPTLSPRVPQPMGTRGTTINLRAAVPPP--------------SGQQTNQGSP 571

  Fly   644 EFNAPNVMSIN-------LPVHVMTTVRQAPAAGSNETADQSASESSSPE-SAPASGNGESPNAA 700
            ..::|....::       ||:|               |.||:::.|||.. |...|.:..|.::.
Zfish   572 MTSSPLTQMVSGLVGQLLLPLH---------------TGDQTSTTSSSHSFSFSTSSSTSSSSSF 621

  Fly   701 STSSGTRSGDQRANTLPTTATQTRST-SRPQIQIGGNNNWGGRIAPTHTAFDRFLPCNSHHIREP 764
            |::|...|.   |||...|:|.|.|| |..|.|..|.   |..:|
Zfish   622 SSASPPLSS---ANTSGQTSTHTTSTASVGQAQESGP---GDNLA-------------------- 660

  Fly   765 EQLLQNNSTSRSTSTAPAGGATVVPPTSAAVTRPVTTGRIQRGSNTI---RPMWSSRRQRPASEQ 826
             |||    .|.....|.|||.......|..||.|.....||..|..|   :|::.|..|:|...|
Zfish   661 -QLL----GSLLGGAAGAGGGVSGATPSITVTVPGVPAFIQGLSEFIQSGQPVFPSPNQQPPPSQ 720

  Fly   827 LSNLGPAAWAQAQTQTTHIPSAHVGAGSTNGAGVGAGRVRPVGGSTINRDRLATRTAHVGGGSTN 891
            .:.                |||..|...|.....||..:.|...:.|.:..|:|....:|.|..|
Zfish   721 ATP----------------PSAPSGPAPTTAPSGGAETLSPELFTGIVQGVLSTMMGSLGAGQGN 769

  Fly   892 GGLPSGRRGRLQAATSRLSRHLPTQLANFLIN-NMRNNAPTASVGSAVAAVGDTAASPSGEAAPI 955
                                  ...:|.|:.. :..:|..|...|.||...||..:        :
Zfish   770 ----------------------TESIAQFIQRLSQTSNLFTPGAGDAVGFFGDLLS--------L 804

  Fly   956 ASTTPAAPLQTVLPTSTPTPRGDSNNLRSQLRTFLNDSLFVGVPINEQTIPGAIGRALDWFGESL 1020
            ...:.:.....:|....|.|   .:.::.||..|..:....|....:..|..|        .|.|
Zfish   805 VCQSFSMVDMVLLLHGNPQP---LSRIQPQLTAFFTEHYLQGREPTDANIASA--------SEDL 858

  Fly  1021 V-YLPQYERPEYNS---RDSVCNILRVSLRLI----------IELCNGAPAGVDSAQFEQSLKQI 1071
            : .|.:|....:::   |:.| :|::.::..:          |..|      .|:. |.|.|..:
Zfish   859 INELEEYIAESFSTVTVREGV-DIIQTNMSFLRQQFTRMATHILRC------TDNT-FGQRLLYL 915

  Fly  1072 CDQFRKRLYSVLFLCLGSANAELYWRQLMRLLCAPMRSNFR------NEALQFLCIYIDPTI--- 1127
            |.|       .||.||.           :.|.|  :|...|      |..::.:...::|::
Zfish   916 CTQ-------GLFECLA-----------LNLYC--LRGEQRALTTVINHRIRRMSAEVNPSLVNW 960

  Fly  1128 ----------------PAQTDTVDAQQFLVLRSIQAAPPTAADEPFVAPPPFAFNPQQQQLQEQT 1176
                            |...|.:  |.:::....::|..|.|.             .|...|.|.
Zfish   961 LTSMMSMRLHVILEHNPVTEDQI--QHYVIYTQSESARRTEAG-------------SQSSQQSQN 1010

  Fly  1177 LDTDVEMSEVTAS-------GSNSSPADELP----------AVIVG----------SEPWHMSFP 1214
            ::.:..:|...|:       .:..:..||.|          ||.:.          :|||..:.|
Zfish  1011 MNVEEGLSPAPATTAEEALRSTGDTDGDEAPGRPSAEETRGAVAMATTEREESTGEAEPWAATVP 1075

  Fly  1215 NDWLPVITRDLQTQAEQSNRPQPPFSDAYISGMSAKRRKIIQSEKPTASVECLIANGVQRAIQSV 1279
            .:|:|:|.||:.||.:.  :.|||.||||:.||.|||||..|.|.|..|    :...|.||.::.
Zfish  1076 PEWVPIIRRDMLTQRKM--KAQPPLSDAYMHGMPAKRRKTAQGEGPHLS----LTEAVSRAARTA 1134

  Fly  1280 GLGGSNGGSALNASISMDTVIGSIAHDSTIQAAYTDAVRNSLKERTERDVDFKTSKYPQIAK-FT 1343
            |:.......:|...:          ....:|.||...|::.:|:|...|.|:...::|...: |:
Zfish  1135 GVRPVTAPDSLQGEL----------ETPELQEAYAQQVKSDIKKRLSDDPDYNHQRFPNTHRVFS 1189

  Fly  1344 E 1344
            |
Zfish  1190 E 1190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7546	NP_001137904.1	Ubl_BAG6	3..73	CDD:340507	32/69 (46%)
		BAG6	350..457	CDD:463449	36/122 (30%)
bag6l	XP_017207757.1	Ubl_BAG6	7..77	CDD:340507	32/69 (46%)
		BAG6	264..382	CDD:463449	36/117 (31%)
		PRK07764	<372..565	CDD:236090	42/243 (17%)