DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8539 and Agbl3

DIOPT Version :9

Sequence 1:	NP_001261520.1	Gene:	CG8539 / 38842	FlyBaseID:	FBgn0035791	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001276585.1	Gene:	Agbl3 / 76223	MGIID:	1923473	Length:	1006	Species:	Mus musculus

Alignment Length:	242	Identity:	53/242 - (21%)
Similarity:	94/242 - (38%)	Gaps:	77/242 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 SYDGIMQYLDELALSHSN---------RVTLKDVARTYENRALKMAIIT---NGDGRPGKRVIFL 92
            :|..:.:||..:   :|:         ||....:||   |....:.|.|   ..|.:  ::.:.|
Mouse   307 TYSNLQEYLSGI---NSDPVRSKFCKIRVLCHTLAR---NMVYVLTITTPLKTSDSK--RKAVIL 363

  Fly    93 DAALHSRE----WMTPAAALLTIHKLVVEF--AENSD--LLTD-YDWHIMPLANPDGYEYSRNTE 148
            .|.:|..|    |         |.|..:::  .::||  ||.| :.:.::|:.||||....
Mouse   364 TARVHPGETNSSW---------IMKGFLDYILGDSSDARLLRDTFIFKVVPMLNPDGVIVG---- 415

  Fly   149 RYWRNTRTPNGGNCFGTNLNRNFAVDWNVGFPELKDPCDENYAGSSPFSEVEARTVRDIMHGLVE 213
                |.|.    :..|.:||||:.......||.:                   ...|::::.|:|
Mouse   416 ----NYRC----SLAGRDLNRNYTSLLKESFPSV-------------------WYTRNMINRLME 453

  Fly   214 SKRAVMYLSLHTANR--SVFYPWVYDTDPVSNQKEHDEIGRFVADRI 258
            .:..::|..||..:|  ::|   :|..|..|..|..   |.::..||
Mouse   454 KREVILYCDLHGHSRKQNIF---MYGCDGSSRSKTK---GLYLQQRI 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8539	NP_001261520.1	M14_CP_A-B_like	38..335	CDD:199844	53/242 (22%)
Agbl3	NP_001276585.1	M14_AGBL2-3_like	315..576	CDD:133117	51/234 (22%)
Agbl3	NP_001276585.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	790..810
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900