DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8539 and AGBL5

DIOPT Version :9

Sequence 1:	NP_001261520.1	Gene:	CG8539 / 38842	FlyBaseID:	FBgn0035791	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_068603.4	Gene:	AGBL5 / 60509	HGNCID:	26147	Length:	886	Species:	Homo sapiens

Alignment Length:	154	Identity:	35/154 - (22%)
Similarity:	54/154 - (35%)	Gaps:	59/154 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 SYDGIMQYLDELALSHSNRVTLKDVARTYENR--ALKMAIITNGDGRP----GKRVIFLDAALHS 98
            |.||:...|..:...|..|          |:|  .|:.........||    |||:.||.:.:|.
Human   199 SLDGLRVDLLTITSCHGLR----------EDREPRLEQLFPDTSTPRPFRFAGKRIFFLSSRVHP 253

  Fly    99 REWMTPAAALL----------------TIHKLVVEFAENSDLLTDYDWHIMPLANPDGYEYSRNT 147
            .|  ||::.:.                |:.:|.|             :.::|:.||||....
Human   254 GE--TPSSFVFNGFLDFILRPDDPRAQTLRRLFV-------------FKLIPMLNPDGVVRG--- 300

  Fly   148 ERYWRNTRTPNGGNCFGTNLNRNF 171
             .|..::|        |.||||.:
Human   301 -HYRTDSR--------GVNLNRQY 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8539	NP_001261520.1	M14_CP_A-B_like	38..335	CDD:199844	35/154 (23%)
AGBL5	NP_068603.4	M14_AGBL5_like	176..568	CDD:199860	35/154 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	344..364
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	605..734
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	784..848
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810