back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8539 and CPA4

DIOPT Version :9

Sequence 1:	NP_001261520.1	Gene:	CG8539 / 38842	FlyBaseID:	FBgn0035791	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_057436.2	Gene:	CPA4 / 51200	HGNCID:	15740	Length:	421	Species:	Homo sapiens

Alignment Length:	347	Identity:	104/347 - (29%)
Similarity:	166/347 - (47%)	Gaps:	35/347 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GIVVLVTIVVNQL---SEAREVRRRRGLMLQLDN-----YLSYDGIMQYLDELALSHSNRVTLKD 63
            |:...|||...|.   :|..|::...|.....:|     |.|.:.|...:|.:|....:......
Human    84 GLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSLEAIYHEMDNIAADFPDLARRVK 148

  Fly    64 VARTYENRALKMAIITNGDG--RPGKRVIFLDAALHSREWMTPAAALLTIHKLVVEFAEN---SD 123
            :..::|||.:.:...:.|.|  ||   .::|:|.:|||||::.|.|:.|..|:|.::..:   :.
Human   149 IGHSFENRPMYVLKFSTGKGVRRP---AVWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITS 210

  Fly   124 LLTDYDWHIMPLANPDGYEYSRNTERYWRNTRTPN-GGNCFGTNLNRNFAVDWNVGFP---ELKD 184
            :|...|..::|:||||||.|::...|.||.||:.| |.:|.|.:.|||    ||..|.   ...:
Human   211 ILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPNRN----WNASFAGKGASDN 271

  Fly   185 PCDENYAGSSPFSEVEARTVRDIM--HGLVESKRAVMYLSLHTANRSVFYPWVYDTDPVSNQKEH 247
            ||.|.|.|....||||.::|.|.:  ||..:.     ::.||:.::.:.||:.|......:.:|.
Human   272 PCSEVYHGPHANSEVEVKSVVDFIQKHGNFKG-----FIDLHSYSQLLMYPYGYSVKKAPDAEEL 331

  Fly   248 DEIGRFVADRILQSTGTFIKTWQYAKYAGTFGGTSMDYALLAGFPLSFVFEMSGTGRDHVEYKFF 312
            |::.|..|..:...:||..:............|:|:|:|...|...:|.||:..||    .|.|.
Human   332 DKVARLAAKALASVSGTEYQVGPTCTTVYPASGSSIDWAYDNGIKFAFTFELRDTG----TYGFL 392

  Fly   313 PPARDIRHLAEESWTGIKAFAE 334
            .||..|...|||:|.|:|...|
Human   393 LPANQIIPTAEETWLGLKTIME 414

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.