DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8539 and CG14820

DIOPT Version :9

Sequence 1:	NP_001261520.1	Gene:	CG8539 / 38842	FlyBaseID:	FBgn0035791	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_648060.1	Gene:	CG14820 / 38754	FlyBaseID:	FBgn0035718	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	326	Identity:	86/326 - (26%)
Similarity:	150/326 - (46%)	Gaps:	51/326 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 RRRGLMLQLDNYLSYDGIMQYLDELALSHSNRVTLKDVARTYENRALKMAIITNGDGRPGKRVIF 91
            ::|...::...:.:.:.|..:||.:...:.:.||...:..:||.|.::...|:..:|.|   .:|
  Fly   104 KQRITSMEWTQFHTLEEIYAWLDVIEDRYPDIVTPFTIGNSYEGRPIRGVKISYKEGNP---AVF 165

  Fly    92 LDAALHSREWMTPAAALLTIHKLVVEFAEN---SDLLTDYDWHIMPLANPDGYEYSRNTERYWRN 153
            :::.:|:|||:|.|.....|.:|:|  ..|   .|:..:.||:|:|:.|.||:.||...||.||.
  Fly   166 IESNIHAREWITSATITYFIDELLV--PRNPAVRDIAQNVDWYIIPVLNTDGFAYSHEVERLWRK 228

  Fly   154 TRTPNG--GNCFGTNLNRNFAVDWNVGFPELKDPCDENYAGSSPFSEVEARTVRDIMHGLVESKR 216
            :|.|:.  |.|.||:|||||...|.:...| .|||.:.|||.||.|:.|...:...::..:....
  Fly   229 SRLPSDPTGECIGTDLNRNFDYLWMLTGAE-SDPCSQLYAGPSPESDPEISQLTAYINNSIPEGT 292

  Fly   217 AVMYLSLHTANRSVFYPWVYDT-DPVSNQKEHDEIGRFVADRILQSTGTFIKTWQYAKYAGTFGG 280
            ..:|:|||:..:.|..||.:.. :...:..:...:.:..:|.:.:..||..          |:|.
  Fly   293 IKIYISLHSYGQYVLSPWGHTALEFPEHYPQMMHVAKGFSDALYRRYGTVF----------TYGS 347

  Fly   281 TSMDYALLAGFPLSFVFEMSGTG------------------RDHVEYKFFPPARDIRHLAEESWT 327
            ::           :.::|:||:|                  ||..|..|..|..||..:|.|...
  Fly   348 SA-----------TTLYEVSGSGKEWAYAVKNIKIHYTIELRDKGELGFVLPPEDIIPVAREVTE 401

  Fly   328 G 328
            |
  Fly   402 G 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8539	NP_001261520.1	M14_CP_A-B_like	38..335	CDD:199844	85/315 (27%)
CG14820	NP_648060.1	Propep_M14	31..100	CDD:280416
CG14820	NP_648060.1	M14_CP_A-B_like	115..410	CDD:199844	85/315 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466988
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850