DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8539 and CG12374

DIOPT Version :9

Sequence 1:	NP_001261520.1	Gene:	CG8539 / 38842	FlyBaseID:	FBgn0035791	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_610819.1	Gene:	CG12374 / 36410	FlyBaseID:	FBgn0033774	Length:	422	Species:	Drosophila melanogaster

Alignment Length:	326	Identity:	88/326 - (26%)
Similarity:	156/326 - (47%)	Gaps:	39/326 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 LQLDNYLSYDGIMQYLDELALSHSNRVTLKDVARTYENRALKMAIITNGDGRPGKRVIFLDAALH 97
            ::.:.|.:.|.|..::|:...:| :.:..|.:.::||.|.:|...::.   |.|.:.|||:..:|
  Fly   113 MEWETYHTLDTIYDWIDQECAAH-DFLECKVIGQSYEGRDIKSIRLSK---RSGNKAIFLEGNIH 173

  Fly    98 SREWMTPAAALLTIHKLV-VEFAENSDLLTDYDWHIMPLANPDGYEYSRNTERYWRNTRTPNG-- 159
            :.||::.|.....:::|: .|..|...|..:|||.::|:.||||:.|:...||.||..|.|||
  Fly   174 AMEWISSATVTFLLNQLINSEDPEMQRLSEEYDWIVVPMVNPDGFVYTHEVERLWRKNRRPNGYR 238

  Fly   160 ---GNCFGTNLNRNFAVDWNVGFPELKDPCDENYAGSSPFSEVEARTVRDIM----HGLVESKRA 217
               |:|:|.::||||...|......:.:|||..:.|..|.:|||..::::.:    .|.:.|
  Fly   239 NESGDCYGIDMNRNFDYHWGGAGWNIDEPCDHWFGGEEPNTEVEIISLQNFVSSFEDGYIRS--- 300

  Fly   218 VMYLSLHTANRSVFYPWVY-DTDPVSNQKEHDEIGRFVADRILQSTGTFIKTWQYAKYAGTFG-- 279
              |::.|...:.|..|:.: :|:...|.::...|....:|......|:   |:.|    |..|
  Fly   301 --YMAYHAYGQYVLLPYGHSNTEFPPNYEQMKRIAAAFSDAAADVYGS---TFTY----GASGLL 356

  Fly   280 -----GTSMDYAL-LAGFPLSFVFEMSGTGRDHVEYKFFPPARDIRHLAEESWTGIKAFAEKTIE 338
                 |.:.|:|. :...|.:...|:    ||...:.||.|:..|..:..|...|:||...|..|
  Fly   357 NYVVSGAAKDWAYGVKKIPFTCTVEL----RDKGTFGFFLPSNQITEVGLEVTAGLKALVNKAAE 417

  Fly   339 K 339
            :
  Fly   418 E 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8539	NP_001261520.1	M14_CP_A-B_like	38..335	CDD:199844	86/315 (27%)
CG12374	NP_610819.1	Propep_M14	34..104	CDD:280416
CG12374	NP_610819.1	M14_CP_A-B_like	118..415	CDD:199844	86/316 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466991
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850