DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8539 and CG7025

DIOPT Version :9

Sequence 1:	NP_001261520.1	Gene:	CG8539 / 38842	FlyBaseID:	FBgn0035791	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster

Alignment Length:	330	Identity:	93/330 - (28%)
Similarity:	156/330 - (47%)	Gaps:	34/330 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 EAREVRRRRGLMLQLDNYLSYDGIMQYLDELALSHSNRVTLKDVARTYENRALKMAIITNGDGRP 85
            ||..::..|........|.|...|..:||::..::........|.::||.|.::...|:.....|
  Fly   106 EAANLKASRDGTFGWTKYNSLAEIYAWLDDILAAYPTITESFIVGQSYEGRTIRGIKISYKSNNP 170

  Fly    86 GKRVIFLDAALHSREWMTPAAA-------LLTIHKLVVEFAENSDLLTDYDWHIMPLANPDGYEY 143
            |   :.:::.:|:|||:|.|.|       |.:..:||.:.|||      :||:|:|:.|.||:.|
  Fly   171 G---VLIESNIHAREWITSATATWLINEFLTSTDELVRDLAEN------HDWYIVPVLNVDGFVY 226

  Fly   144 SRNTERYWRNTRTPNG-GNCFGTNLNRNFAVDWNVGFPELKDPCDENYAGSSPFSEVEARTVRDI 207
            :...:|.||.||.|:. .:|.|.:.|||:...|........:||.|:|.|..||||.|.:.:.:.
  Fly   227 THEKDRMWRKTRQPSEISSCIGADPNRNYDSHWMENEGASSNPCAEDYGGPKPFSEPEIQAMSEF 291

  Fly   208 MHGLVESKRAVMYLSLHTANRSVFYPWVYDTDPV-SNQKEHDEIGRFVADRILQST--GTFIKTW 269
            :.. ::.|..|: |:.|:.::.:..|:.:..:.. .|..:..|:.:...|.: :|.  ||   .:
  Fly   292 VIS-IKDKINVL-LAFHSYSQLLLSPYGHTKEEFPPNFDDMMEVAKAYGDAV-ESLPYGT---VY 350

  Fly   270 QYAKYAGTF---GGTSMDYAL-LAGFPLSFVFEMSGTGRDHVEYKFFPPARDIRHLAEESWTGIK 330
            :|...||..   .|.::|:|. ..|..:|:..|...|||    |.|..|...|...|||:..||.
  Fly   351 RYGSAAGILYPASGATIDWAYNEQGVEISYTIEFRDTGR----YGFILPPVHIIPNAEEALIGIA 411

  Fly   331 AFAEK 335
            |..||
  Fly   412 ALLEK 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8539	NP_001261520.1	M14_CP_A-B_like	38..335	CDD:199844	88/311 (28%)
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	88/311 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466990
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850