DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8539 and CG18585

DIOPT Version :9

Sequence 1:	NP_001261520.1	Gene:	CG8539 / 38842	FlyBaseID:	FBgn0035791	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001260213.1	Gene:	CG18585 / 34041	FlyBaseID:	FBgn0031929	Length:	422	Species:	Drosophila melanogaster

Alignment Length:	313	Identity:	101/313 - (32%)
Similarity:	158/313 - (50%)	Gaps:	28/313 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 YLSYDGIMQYLDELALSHSNRVTLKDVARTYENRALKMAIITNGDGRPGKRVIFLDAALHSREWM 102
            |...:.|..:|||:..::.:......|.::||.|.::...|::..|.||   ||:::.:|:|||:
  Fly   122 YYELEEIEAWLDEILNAYPSVTEEFIVGKSYEGRTIRGIKISHKAGNPG---IFIESNIHAREWI 183

  Fly   103 TPAAALLTIHKLVV-EFAENSDLLTDYDWHIMPLANPDGYEYSRNTERYWRNTRTPNGGN-CFGT 165
            |.|:|...|::|:. |.|:...|..:|||||:|:.|.||:|||...:|.||.||.|:..| |.|.
  Fly   184 TSASATWFINQLLTSEDADVRSLADNYDWHIIPVFNVDGFEYSHKKDRMWRKTRQPHATNACIGA 248

  Fly   166 NLNRNFAVDW--NVGFPELKDPCDENYAGSSPFSEVEARTVRDIMHGLVESKRAVMYLSLHTANR 228
            :.||||...|  |.|..:  :||.|.:||.:|.||.||:.:.:.:..:.:  :..:|:|.|:..:
  Fly   249 DANRNFDSYWLQNNGASD--NPCSETFAGDNPESEPEAKALVEYLTKIQD--QISVYISFHSYGQ 309

  Fly   229 SVFYPWVYDTDPV-SNQKEHDEIGRFVADRI-LQSTGTFIKTWQYAK-----YAGTFGGTSMDYA 286
            .:..|:.:..:.. .|..:...||:..||.| ....||   .:||..     |..|  |||:|:.
  Fly   310 YLLSPYGHTNEEFPENYNDILTIGKAFADAIEALPYGT---VYQYGSTADVLYVAT--GTSVDWV 369

  Fly   287 L-LAGFPLSFVFEMSGTGRDHVEYKFFPPARDIRHLAEESWTGIKAFAEKTIE 338
            . ..|..:.:..|....||    |.|..|...|....||...|:.|..|||.|
  Fly   370 FNELGKKIGYTIEYRDKGR----YGFILPPVQIIPNCEELMVGMLALIEKTKE 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8539	NP_001261520.1	M14_CP_A-B_like	38..335	CDD:199844	97/308 (31%)
CG18585	NP_001260213.1	Propep_M14	34..105	CDD:280416
CG18585	NP_001260213.1	M14_CP_A-B_like	122..415	CDD:199844	97/308 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466989
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850