DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8539 and suro-1

DIOPT Version :9

Sequence 1:	NP_001261520.1	Gene:	CG8539 / 38842	FlyBaseID:	FBgn0035791	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_492177.2	Gene:	suro-1 / 172557	WormBaseID:	WBGene00011235	Length:	664	Species:	Caenorhabditis elegans

Alignment Length:	356	Identity:	89/356 - (25%)
Similarity:	159/356 - (44%)	Gaps:	53/356 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 NYLSYDGIMQYLDELALSHSNRVTLKDVARTYENRALKMAIITNGDGRPGKRVIFLDAALHSREW 101
            :|.||..:::|:..:...:.....:..:..|:|.:.:: .:.........||.:::|..:|:|||
Worm   160 DYASYADMVKYMRTIEFYYPRIAKIVRIGATHEGKPIE-GLKIGARSSHKKRAVWVDGNIHAREW 223

  Fly   102 MTPAAALLTIHKLVVEFAENSDLLTDY----DWHIMPLANPDGYEYSRN----TERYWRNTRTPN 158
            .:...||..|::||.|:.:::. :|:|    |::|:|..|||||||:|.    |.|.||..|:|.
Worm   224 ASSHTALYFINQLVSEYGKDAQ-ITNYVDTLDFYIVPCLNPDGYEYTRTSPIPTVRLWRKNRSPE 287

  Fly   159 -------GGN--CFGTNLNRNFAVDWNVGFPELKDPCDENYAGSSPFSEVEARTVRDIMHGLVES 214
                   ||.  |.|.:|||||...| .......:||...|.|...|||.|.|.||:.:......
Worm   288 LCRPSLWGGEKCCRGVDLNRNFRFHW-AERGSSYEPCSNIYHGEEVFSEPETRAVRNFLATPEMK 351

  Fly   215 KRAVMYLSLHTANRSVFYPWVYDTDPVSNQKEH--DEIG------RFVADRILQSTGTFIKTWQY 271
            .|...:::||    |....|:|   |.|:::::  ::||      |...:|:.:..||..:....
Worm   352 DRVDAFVTLH----SYAQLWIY---PYSHEEQNYPEDIGELRKTARKAINRLSRVYGTNYRMGTG 409

  Fly   272 AKYAGTFGGTSMDYALLAGFPLSFVFEMSGTGRDHVEYKFFPPARDIRHLAEESWTGIKAFAEKT 336
            |.......|.|.|:|..| ..:.:|:.:....:..:...|....:::...|.|::.|.:...:..
Worm   410 ADTLSPAAGGSDDWAKSA-LNVKYVYLIELRPQMELSNGFILHKKELIPTAVETFEGFREVVDAV 473

  Fly   337 IEKYPPSRVISYNPMVKLAENAATRNLGFNS 367
                             |..|.:|.::|.:|
Worm   474 -----------------LTLNNSTSSIGLSS 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8539	NP_001261520.1	M14_CP_A-B_like	38..335	CDD:199844	84/321 (26%)
suro-1	NP_492177.2	Propep_M14	39..110	CDD:280416
		M14_CP_A-B_like	161..473	CDD:199844	84/322 (26%)
		ShK	620..657	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920