DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8539 and Y47G6A.19

DIOPT Version :9

Sequence 1:	NP_001261520.1	Gene:	CG8539 / 38842	FlyBaseID:	FBgn0035791	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001379340.1	Gene:	Y47G6A.19 / 171921	WormBaseID:	WBGene00021645	Length:	509	Species:	Caenorhabditis elegans

Alignment Length:	350	Identity:	98/350 - (28%)
Similarity:	152/350 - (43%)	Gaps:	60/350 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 LQLDNYLSYDGIMQYLDELALSHSNRVTLKDVARTYENR---ALKMAIITNGDGRPGKRVIFLDA 94
            |::..|.||..:..:|:.:|.:..:...|..|..|.|.|   .||.     |...|.|:::.:||
Worm   129 LRMGEYYSYSVLSTWLERIAENMPDIAKLIKVGTTIEGRDILGLKF-----GKDTPDKKIVVIDA 188

  Fly    95 ALHSREWMTPAAALLTIHKLVVEFAENSDLLTDY----DWHIMPLANPDGYEYSRNTE-----RY 150
            .:|:|||.....|...|: |:|...|....:.:|    ..:|:|:.|||||||:|..:     |.
Worm   189 GIHAREWAAIHTASYFIN-LIVNGREEDPQIQNYLDNIVLYIIPVLNPDGYEYTRTDKTNPRARM 252

  Fly   151 WRNTRTP--------NGGNCFGTNLNRNFAVDWNVGFPEL---KDPCDENYAGSSPFSEVEARTV 204
            ||.:|:|        ....|.|.:|||||    :..|.|:   :.||.|.|.|.|.|||.|::..
Worm   253 WRKSRSPKACAFDGVRNSCCMGVDLNRNF----DFRFSEIGASRYPCSEIYHGPSAFSEPESKAY 313

  Fly   205 RDIMHGLVESKRAVMYLSLHTANRSVFY----------PWVYDTDPVSNQKEHDEIGRFVADRIL 259
            ...:..|  ..|...|::||:.::...|          |.:.:|..|: .|...|:||....:..
Worm   314 SQFLTSL--KGRLEAYITLHSYSQLWIYSYSHRKFTYAPDIEETRRVA-AKAVQELGRMYGTKYR 375

  Fly   260 QSTGTFIKTWQYAKYAGTFGGTSMDYAL-LAGFPLSFVFEMSGTGRDHVEYKFFPPARDIRHL-- 321
            ..||..|      .||  |.|.|.|:|. ......|:..|:.......:|:..|  ..|...|
Worm   376 HGTGPEI------IYA--FSGGSTDWAKETLKIKYSYTIELRPGYEGIIEWNGF--VLDKNQLIP 430

  Fly   322 -AEESWTGIKAFAEKTIEKYPPSRV 345
             |:|:|.|:....::...::..|||
Worm   431 TAKETWAGVTVVLDEVTNQWKSSRV 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8539	NP_001261520.1	M14_CP_A-B_like	38..335	CDD:199844	94/333 (28%)
Y47G6A.19	NP_001379340.1	Propep_M14	32..102	CDD:396700
		M14_CP_A-B_like	134..446	CDD:349433	94/334 (28%)
		ShK	467..504	CDD:396228
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160018
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950