DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8539 and T06A4.3

DIOPT Version :9

Sequence 1:	NP_001261520.1	Gene:	CG8539 / 38842	FlyBaseID:	FBgn0035791	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001021611.1	Gene:	T06A4.3 / 171668	WormBaseID:	WBGene00020283	Length:	505	Species:	Caenorhabditis elegans

Alignment Length:	379	Identity:	104/379 - (27%)
Similarity:	166/379 - (43%)	Gaps:	74/379 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 VNQLSEAREVRRRRGLMLQLDN------------------------YLSYDGIMQYLDELALSHS 56
            ||.:|..:.:....||:.:.:|                        |.||..:..::.:|.:.:.
Worm    82 VNDISYIKTIDDVEGLITKHENNKTLSNMFPRLWDDSSSAHYDFHTYGSYQRMTDWMKQLVVKYP 146

  Fly    57 NRVTLKDVARTYENRALKMAIITNGDGRPGKRVIFLDAALHSREWMTPAAALLTIHKLVVEFAEN 121
            ..|....:.:|.|.|.:. .:...||.|. |::.::|..:|:|||..|..||..||:|.....|.
Worm   147 KMVQYISIGKTTEGRNID-GVEIGGDSRT-KKIFWIDGGIHAREWAAPHTALFFIHQLTSRANEP 209

  Fly   122 --SDLLTDYDWHIMPLANPDGYEYSRNTE----RYWRNTRTPN-------GGN--CFGTNLNRNF 171
              ..||.:..:.::|..||||||::|::.    |.||..|:..       |.|  |.|.:|||||
Worm   210 GIKKLLNEITFVVVPCLNPDGYEFTRSSTNPHVRLWRKNRSKMQCRKDIWGRNRCCRGVDLNRNF 274

  Fly   172 AVDWNVGFPE---LKDPCDENYAGSSPFSEVEARTVRDIMHGLVESKRAVMYLSLHTANRSVFYP 233
              |::  |.|   ..|||.|.|.|.|||||.||:.|||.:.......|...|::|||.::...:|
Worm   275 --DFH--FRESGTSDDPCSEIYQGPSPFSEPEAKAVRDALLSQRYKGRTDAYITLHTYSQIWIHP 335

  Fly   234 WVYDTDPVSNQ-KEHDEIGRFVADRILQSTGTFIKTWQYAKYAGT-----FGGTSMDYALLAGFP 292
            :.:..|..... |:..|:|:..|..:.:..||     :|...:|.     ..|.|.|:|.... .
Worm   336 YGHKKDAYPGDIKDLYEVGKKAAQALKRVYGT-----KYVVGSGADTLYPASGGSEDWAKHEA-K 394

  Fly   293 LSFVF-------EMSGTGRDHVEYKFFPPARDIRHLAEESWTGIKAFAEKTIEK 339
            :.||:       |.:..|....|.:..|.||       |:|.|::..||..:::
Worm   395 VKFVYLLELRPDEKNWDGFILDEKELIPTAR-------ETWEGVRVVAEAVLDR 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8539	NP_001261520.1	M14_CP_A-B_like	38..335	CDD:199844	97/327 (30%)
T06A4.3	NP_001021611.1	Propep_M14	31..98	CDD:366995	4/15 (27%)
		M14_CP_A-B_like	128..438	CDD:349433	98/328 (30%)
		ShK	468..505	CDD:366702
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020