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Protein Alignment CG8539 and CPA2

DIOPT Version :9

Sequence 1:	NP_001261520.1	Gene:	CG8539 / 38842	FlyBaseID:	FBgn0035791	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001860.2	Gene:	CPA2 / 1358	HGNCID:	2297	Length:	419	Species:	Homo sapiens

Alignment Length:	318	Identity:	101/318 - (31%)
Similarity:	163/318 - (51%)	Gaps:	25/318 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RRRRGLMLQLDNYLSYDGIMQYLDELALSHSNRVTLKDVARTYENRALKMAIITNGDGRPGKRVI 90
            ||.|........|.:.:.|.|.:|.|...|...|:..::..::|||.:.:...:.|..:|   .|
Human   111 RRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKP---AI 172

  Fly    91 FLDAALHSREWMTPAAALLTIHKLVVEFAEN---SDLLTDYDWHIMPLANPDGYEYSRNTERYWR 152
            :|||.:|:|||:|.|.||.|.:|:|.::.::   :.:|...|..::|:.|||||.:|:...|.||
Human   173 WLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 237

  Fly   153 NTRTP-NGGNCFGTNLNRNFAVDWNVGF---PELKDPCDENYAGSSPFSEVEARTVRDIM--HGL 211
            .||:. :|..|.|.:.|||    |:.||   ....:||.::|.|.|..||||.:::.|.:  ||.
Human   238 KTRSKVSGSLCVGVDPNRN----WDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGK 298

  Fly   212 VESKRAVMYLSLHTANRSVFYPWVYDTDPVSNQKEHDEIGRFVADRILQSTGTFIKTWQYAKYAG 276
            |::     :::||:.::.:.:|:.|....:.:..|..|:.:..|..:....||..|.........
Human   299 VKA-----FITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIY 358

  Fly   277 TFGGTSMDYALLAGFPLSFVFEMSGTGRDHVEYKFFPPARDIRHLAEESWTGIKAFAE 334
            ...|.|:|::...|...||.||:..|||    |.|..|||.|...|||:|.|:||..|
Human   359 QASGGSIDWSYDYGIKYSFAFELRDTGR----YGFLLPARQILPTAEETWLGLKAIME 412

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.