DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d8 and CYP702A5

DIOPT Version :9

Sequence 1:	NP_523961.2	Gene:	Cyp4d8 / 38841	FlyBaseID:	FBgn0015033	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_001078393.1	Gene:	CYP702A5 / 827206	AraportID:	AT4G15393	Length:	467	Species:	Arabidopsis thaliana

Alignment Length:	523	Identity:	123/523 - (23%)
Similarity:	216/523 - (41%)	Gaps:	108/523 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLLFLLVVLLFGAGWIIHLGQADRRRKVANLPGPICPPLIGA----MQLMLRLNPKTFIKVGREY 61
            :::.|:||.|  ..||..........|:.  ||.:..|:||.    |:|...:...||:|   |.
plant    10 VIVSLIVVKL--CHWIYQWKNPKGNGKLP--PGSMGYPIIGETFEFMKLHDAIQLPTFVK---EK 67

  Fly    62 VLKFGHLQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNGLLLSDGKVWHQRR 126
            :|:.|.:.|..:|...:|:|.|..||.: ::...|:...|  |.|.:..|...|..: |..|:..
plant    68 LLRHGPVFRTSLFGGKVIISTDIGLNME-IAKTNHIPGMP--KSLERLFGATNLFVN-KDTHKHA 128

  Fly   127 KIITPTFHFS--ILEQFVEVFDQQSNICVQRLAQKANGNTFDVYRSICAAALDIIAETAMGTKIY 189
            :.:|..|..|  :..:.::..|..:...::..|:|   ...||..:.....::.:::..||
plant   129 RSLTNQFLGSQALKLRMIQDIDFLARTHMKEGARK---GCLDVKETASKIVIECLSKKVMG---- 186

  Fly   190 AQANESTPYAEAVNECTALLSWRFM--------------SVYLQVELLFTLTHPHLKWRQTQLIR 240
                |..|  ||..|.|  |.|.|.              .||..|:            .:.::::
plant   187 ----EMEP--EAAKELT--LCWTFFPRDWFRFAWNFPGTGVYRIVK------------ARNRMMK 231

  Fly   241 TMQEFTIKVIEKRRQALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTVDGRPLTNDEIREE-VD 304
            .::|..:|     ::|...:..:..:|...|..|         :.||.         ||..| :.
plant   232 VIKETVVK-----KRASGKKLGEFFETIFGDTES---------VTMSI---------EIATEYIF 273

  Fly   305 TFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEE---IVQ-VLGTDRSRPVSIRDLGELKYMECV 365
            |.....::||...|:..:..:|.:|:|..::..|   ||| .:..|.:..::..|...:.:.:.|
plant   274 TLFVLANETTPGVLAATIKLISDNPKVMQELRREHEGIVQDKIKKDETADLTWEDYKSMTFTQMV 338

  Fly   366 IKESLRMYPPVPIVGRKLQTDFKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETFPNPDEFIPERH 430
            |.||||:...||.|.|.:..:.::     ||..|||| .|.:|...||..||.:.:|..|.|.|.
plant   339 INESLRITSTVPTVLRIIDHEIQF-----GDYTIPAG-WIFMGYPYVHFNPEKYDDPLAFNPWRW 397

  Fly   431 ENG--SRVAPFKMIPFSAGPRNCIGQKFAQLEMKMML-------------AKIVREYEL-LPMGQ 479
            :..  |.:.....:||.:|.|.|:|.:|.:|:|.:.:             ..::|.:.| ||.|.
plant   398 KGKDLSTIVSKTYLPFGSGTRLCVGAEFVKLQMAIFIHHLFRYRWSMKAETTLLRRFILVLPRGS 462

  Fly   480 RVE 482
            .|:
plant   463 DVQ 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	104/454 (23%)
CYP702A5	NP_001078393.1	p450	30..448	CDD:386267	111/482 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010