DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d8 and CYP83A1

DIOPT Version :9

Sequence 1:	NP_523961.2	Gene:	Cyp4d8 / 38841	FlyBaseID:	FBgn0015033	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_193113.1	Gene:	CYP83A1 / 827011	AraportID:	AT4G13770	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	532	Identity:	120/532 - (22%)
Similarity:	228/532 - (42%)	Gaps:	83/532 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LLVVLLFGAGWIIHLGQADRRRKVANLPGPICPPLIGAMQLMLRLNPKTFIKVGREYVLKFGHLQ 69
            |..||||      .|.|..:.::....|||...|:||.:..:.:|||:.|.   ..:..|:|.:.
plant    11 LAAVLLF------FLYQKPKTKRYKLPPGPSPLPVIGNLLQLQKLNPQRFF---AGWAKKYGPIL 66

  Fly    70 RVWIFNRLLIMSGDAELNEQLLSSQE-HLVKHPVYKVLGQWLGNGLLLSDGK----------VWH 123
            ...|.:|.:::...|||.::||.:|: :....|.::      |:. .:|.|:          .:.
plant    67 SYRIGSRTMVVISSAELAKELLKTQDVNFADRPPHR------GHE-FISYGRRDMALNHYTPYYR 124

  Fly   124 QRRK-----IITPTFHFSILEQFVEVFDQQSNICVQRLAQKAN-GNTFDVYRSICAAALDIIAET 182
            :.||     :.:||    .:..|..|.::::...:.::.:.|: ....|:...:......::...
plant   125 EIRKMGMNHLFSPT----RVATFKHVREEEARRMMDKINKAADKSEVVDISELMLTFTNSVVCRQ 185

  Fly   183 AMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQTQLIRTMQEFTI 247
            |.|.|......|...:.:.:....::|...|.|.:.          |:..:     :..:...|.
plant   186 AFGKKYNEDGEEMKRFIKILYGTQSVLGKIFFSDFF----------PYCGF-----LDDLSGLTA 235

  Fly   248 KVIEKRRQALEDQQSKLMDTADEDVGSKR----RMALLDVLLMSTVDGRP----LTNDEIREEVD 304
            .:    ::..|.|.:.:.:..:|.:..||    ..:::| |||.....:|    .|.|.::..:.
plant   236 YM----KECFERQDTYIQEVVNETLDPKRVKPETESMID-LLMGIYKEQPFASEFTVDNVKAVIL 295

  Fly   305 TFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKES 369
            ..:..|.||..:|:.:.:..|.::|:|..|...|:.:.:....|..|:..|:..|.|...::||:
plant   296 DIVVAGTDTAAAAVVWGMTYLMKYPQVLKKAQAEVREYMKEKGSTFVTEDDVKNLPYFRALVKET 360

  Fly   370 LRMYPPVP-IVGRKLQTDFKYTHSVHGDGV-IPAGSEIIIGIFGVHR-QPETFPNPDEFIPER-- 429
            ||:.|.:| ::.|....|.|..      |. ||||:.:.:..:.|.| :.|..||||||.|||
plant   361 LRIEPVIPLLIPRACIQDTKIA------GYDIPAGTTVNVNAWAVSRDEKEWGPNPDEFRPERFL 419

  Fly   430 -HENGSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYEL-LPMGQRVECIVNIVLRSE 492
             .|...:...::.|||.:|.|.|.|.:.....:::..|.::..:.. ||.|.:.:.|...|:
plant   420 EKEVDFKGTDYEFIPFGSGRRMCPGMRLGAAMLEVPYANLLLSFNFKLPNGMKPDDINMDVM--- 481

  Fly   493 TGFQLGMRKRKH 504
            ||  |.|.|.:|
plant   482 TG--LAMHKSQH 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	98/462 (21%)
CYP83A1	NP_193113.1	PLN02966	1..502	CDD:178550	120/532 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910