DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d8 and CYP94D2

DIOPT Version :9

Sequence 1:	NP_523961.2	Gene:	Cyp4d8 / 38841	FlyBaseID:	FBgn0015033	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_191222.1	Gene:	CYP94D2 / 824830	AraportID:	AT3G56630	Length:	499	Species:	Arabidopsis thaliana

Alignment Length:	543	Identity:	135/543 - (24%)
Similarity:	221/543 - (40%)	Gaps:	149/543 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 VANLPGPI----------------CPPLI------GAMQLMLRLNPKTFIKVGREYVL--KFGHL 68
            |.:|||.:                ||...      |.:|.::..||...     ||:|  ||...
plant    37 VGSLPGLVNNRHRFLDWTVETLSRCPTQTAIFRRPGKLQFVMTANPANV-----EYMLKTKFESF 96

  Fly    69 QRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNGLLLSDGKVWHQRRKIITPTF 133
            .:                .|:.:|            :|..:||.|:..|||::|.::||..:..|
plant    97 PK----------------GERFIS------------ILEDFLGRGIFNSDGEMWWKQRKTASYEF 133

  Fly   134 HFSILEQFVEVFDQQSNICVQ-------RLAQKA-NGNTFDV--------YRSICAAALDIIAET 182
            ....|..||     .||:.|:       .||:.| ||...|:        :.:||..|.: :...
plant   134 STKSLRDFV-----MSNVTVEINTRLVPVLAEAATNGKLIDLQDILERFAFDNICKLAFN-VDSA 192

  Fly   183 AMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQTQLI-----RTM 242
            .:|....|..|    :.:|......::|.||.||.            ...|:..:.:     |.:
plant   193 CLGDDGAAGVN----FMQAFETAATIISQRFQSVI------------SYSWKIKKKLNIGSERVL 241

  Fly   243 QEFTIKVIEK-----RRQALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTVDGRPLTNDEI-RE 301
            :| :|.::.|     .|..:|  |.|:.|..::             ||...:....:.:.|| |:
plant   242 RE-SIMIVHKFADEIVRNRIE--QGKVSDHKED-------------LLSRFISKEEMNSPEILRD 290

  Fly   302 EVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQV---LGTDRSRPVSIRDLGELKYME 363
            .|.:|:..|.|||:||||:....||.||||:.|:|:|:..:   .|..........||..:.|:.
plant   291 IVISFILAGRDTTSSALSWFFWLLSMHPEVKDKILQELNSIRERTGKRIGEVYGFEDLKLMNYLH 355

  Fly   364 CVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDGVIPAGS------EIIIGIFGVHRQPETF-PN 421
            ..|.||||:|||||:          .|.|...|.|:|.|:      .|....:.:.|....: .:
plant   356 AAITESLRLYPPVPV----------DTMSCAEDNVLPDGTFIGKDWGISYNAYAMGRMESIWGKD 410

  Fly   422 PDEFIPER---HENGS--RVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREY--ELLPMGQ 479
            .|.|.|||   ..||.  ...|:|...|.||||.|:|::.|.::||.::|.::..:  |:....:
plant   411 CDRFDPERWIDETNGGFRGENPYKFPAFHAGPRMCLGKEMAYIQMKSIVAAVLERFVVEVPGKKE 475

  Fly   480 RVECIVNIVLRSETGFQLGMRKR 502
            |.|.::::.||...|..:.:::|
plant   476 RPEILMSVTLRIRGGLNVRVQER 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	119/474 (25%)
CYP94D2	NP_191222.1	p450	52..499	CDD:299894	131/528 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920