DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d8 and CYP72A7

DIOPT Version :9

Sequence 1:	NP_523961.2	Gene:	Cyp4d8 / 38841	FlyBaseID:	FBgn0015033	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_188079.1	Gene:	CYP72A7 / 820689	AraportID:	AT3G14610	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	477	Identity:	126/477 - (26%)
Similarity:	207/477 - (43%)	Gaps:	76/477 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 DRRRKVANLPGPICPPLIGAMQLMLRLNPKTFIKVGREYVLKFGHLQRVWIFNRLLIMSGDAELN 87
            :.|.|..|:...|.|.|:.....||..:.|||.               :||.....|:..:.|..
plant    64 EARSKPINVTDDITPRLLPLALKMLNSHGKTFF---------------IWIGPLPTIVITNPEQI 113

  Fly    88 EQLLSSQEHLVKHPVYKVLGQWLGNGLLLSDGKVWHQRRKIITPTFHFSILEQFVEVFDQQSNIC 152
            :::.:......|...:.:: :.|..||....|..|...|:||.|.||...::..:..|   .:.|
plant   114 KEVFNKVNDFEKASTFPLI-RLLAGGLASYKGDKWASHRRIINPAFHLEKIKNMIPAF---YHCC 174

  Fly   153 VQRLAQ-------KANGNTFDVYRSICAAALDIIAETAMGTKIYAQANESTPYAEAVNECTALLS 210
            .:.:.|       |.:....||:..:.....|:|:.||.|:..    .|.....:...|...|::
plant   175 SEVVCQWEKLFTDKESPLEVDVWPWLVNMTADVISHTAFGSSY----KEGQRIFQLQGELAELIA 235

  Fly   211 WRFMSVYLQVELLFTLTHPHLKWRQTQLIRTMQEFTIKV-------IEKRRQALEDQQSKLMDTA 268
            ..|...|:          |..::..|:..|.|:....:|       :.||.:|.|     ..:.|
plant   236 QAFKKSYI----------PGSRFYPTKSNRRMKAIDREVDVILRGIVSKREKARE-----AGEPA 285

  Fly   269 DEDVGSKRRMALLDVLLMSTVD---GRPLTNDEIREEVDTFMFEGHDTTTSALSFCLHELSRHPE 330
            ::|        ||.:||.|..:   |..::.:::.:|...|.|.|.:||:..|.:.:..||.|.:
plant   286 NDD--------LLGILLESNSEESQGNGMSVEDVMKECKLFYFAGQETTSVLLVWTMVLLSHHQD 342

  Fly   331 VQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHSVHG 395
            .||:..||::|||| :.::| .:..|..||.|..:..|.||:||||..:.|.:..:.|.     |
plant   343 WQARAREEVMQVLG-ENNKP-DMESLNNLKVMTMIFNEVLRLYPPVAQLKRVVNKEMKL-----G 400

  Fly   396 DGVIPAGSEIIIGIFGVHRQPETF-PNPDEFIPERHENGSRVAPFKMI---PFSAGPRNCIGQKF 456
            :..:|||.:|.:....|.|..|.: .:..:|.|||..:|...|....:   ||..|||.||||.|
plant   401 ELTLPAGIQIYLPTILVQRDTELWGDDAADFKPERFRDGLSKATKNQVSFFPFGWGPRICIGQNF 465

  Fly   457 AQLEMKMMLAKIVRE--YELLP 476
            |.||.||.:|.|:::  :||.|
plant   466 AMLEAKMAMALILQKFSFELSP 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	115/434 (26%)
CYP72A7	NP_188079.1	p450	21..512	CDD:299894	126/477 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860