DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d8 and CYP76C3

DIOPT Version :9

Sequence 1:	NP_523961.2	Gene:	Cyp4d8 / 38841	FlyBaseID:	FBgn0015033	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_182082.2	Gene:	CYP76C3 / 819166	AraportID:	AT2G45580	Length:	515	Species:	Arabidopsis thaliana

Alignment Length:	512	Identity:	119/512 - (23%)
Similarity:	205/512 - (40%)	Gaps:	91/512 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LLFLLVVLLFGAGWIIHLGQADRRRKVAN---LPGPICPPLIGAMQLMLRLNP--------KTFI 55
            |.|||.:..|      ....|..||..:.   .|||...||:|.: ..|..||        ||:
plant    13 LYFLLTLFFF------FFATAKTRRSSSTGTLPPGPPILPLVGNI-FQLGFNPHRSLAAFSKTY- 69

  Fly    56 KVGREYVLKFGHLQRVWIFNRLLIMSGDAELNEQLLSSQEHLV---------------KHPVYKV 105
              |....||.|.|..|.|        ...|..::.|.:.:|::               ||.:.
plant    70 --GPIMSLKLGRLTAVVI--------SSPEAAKEALRTHDHVMSARTFNDALRAFDHHKHSIV-- 122

  Fly   106 LGQWLGNGLLLSDGKVWHQRRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKAN-----GNTF 165
               |      :.....|...:|.||   .:.:..|.::.........|:.|....|     |...
plant   123 ---W------IPPSARWRFLKKTIT---KYLLSPQNLDAIQSLRMRKVEELVSLVNEFRERGEAI 175

  Fly   166 DVYRSICAAALDIIAETAMGTKI--YAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTL-- 226
            |:.|:....:.:||:.......:  |...:.|..:...|...|.:.....:..|.|......|
plant   176 DLARASFVTSFNIISNALFSVDLATYDSNSSSYEFHNTVVHLTDIAGIPNVGDYFQYMRFLDLQG 240

  Fly   227 THPHLKWRQTQLIRTMQEFTIKVIEKR--RQALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTV 289
            |.........:|.|..|||....:.||  |...|.:::..:|..|         :|||:...:..
plant   241 TRKKAVLCIEKLFRVFQEFIDARLAKRFSRTEKEPKEASSIDMLD---------SLLDLTQQNEA 296

  Fly   290 DGRPLTNDEIREEVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIR 354
            :   ||.::::..:......|.||.:|.:.:.:.||.|..|...|...||.||:|  ::..|...
plant   297 E---LTMNDLKHLLLDVFVAGTDTNSSTMEWAMTELFRSTEKMVKAQSEIRQVIG--QNGFVQES 356

  Fly   355 DLGELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETF 419
            |:..|.|::.::||:||::|..|::.||.::|.:    :.| .::|..:::::.::.:.|....:
plant   357 DIPSLPYLQAIVKETLRLHPAAPLIPRKSESDVQ----IMG-FLVPKNTQVVVNVWAIGRDASVW 416

  Fly   420 PNPDEFIPER---HENGSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYE 473
            .||.:|.|||   .|...:...|::|||.:|.|.|.|...|...|.|:||.::..::
plant   417 ENPMKFEPERFLLRETDVKGRDFELIPFGSGRRMCPGISMALKTMHMVLASLLYSFD 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	97/437 (22%)
CYP76C3	NP_182082.2	p450	48..506	CDD:299894	106/471 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010