DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d8 and CYP704A1

DIOPT Version :9

Sequence 1:	NP_523961.2	Gene:	Cyp4d8 / 38841	FlyBaseID:	FBgn0015033	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_850427.2	Gene:	CYP704A1 / 819098	AraportID:	AT2G44890	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	514	Identity:	124/514 - (24%)
Similarity:	217/514 - (42%)	Gaps:	90/514 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 AMQLMLRL------NPKTFIKVGREYVLKFGHLQRVWIFN----------RLL------IMSGDA 84
            |:.|.:|:      |.|.:..|.......|.|..:::.:.          |.|      |.:.|.
plant    22 ALYLTIRIFTGKSRNDKRYTPVHATIFDLFFHSHKLYDYETEIARTKPTFRFLSPGQSEIFTADP 86

  Fly    85 ELNEQLLSSQEH-LVKHPVYKV-LGQWLGNGLLLSDGKVWHQRRKIITPTFHFSILEQF-VEVFD 146
            ...|.:|.::.| ..|.||..| |...||:|:...||:.|.|:||:::..|...:|..| ..||.
plant    87 RNVEHILKTRFHNYSKGPVGTVNLADLLGHGIFAVDGEKWKQQRKLVSFEFSTRVLRNFSYSVFR 151

  Fly   147 QQSNICVQRLAQKA-NGNTFDVYRSICAAALDIIAETAMGTKIYAQ---ANESTPYAEAVNECTA 207
            ..::..|..:|:.| :|.:||....:....||.|.:...|.::...   :.|...:.:|.:|...
plant   152 TSASKLVGFIAEFALSGKSFDFQDMLMKCTLDSIFKVGFGVELGCLDGFSKEGEEFMKAFDEGNG 216

  Fly   208 LLSWRFMSVYLQVELLFTL-THPHLKWRQTQLIRTMQEFTIKVIEKRRQALEDQQSKLMDTADED 271
            ..|.|....:.:::....: :...||    :.|..:.:|...:|..:|:.|..:|:   .:..||
plant   217 ATSSRVTDPFWKLKCFLNIGSESRLK----KSIAIIDKFVYSLITTKRKELSKEQN---TSVRED 274

  Fly   272 VGSKRRMALLDVLLMSTVDGRPLTNDEIREEVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKML 336
            :.||       .||.|..|...:.:..:|:.:...|..|.|||.::||:.|:.|.::|.||.|::
plant   275 ILSK-------FLLESEKDPENMNDKYLRDIILNVMVAGKDTTAASLSWFLYMLCKNPLVQEKIV 332

  Fly   337 EEIVQVLGTDRS--------RPVSIRDLGELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHSV 393
            :||..|..:...        ..|:...|.:::|:...:.|::|:|||||          ::....
plant   333 QEIRDVTSSHEKTTDVNGFIESVTEEALAQMQYLHAALSETMRLYPPVP----------EHMRCA 387

  Fly   394 HGDGVIPAGSEIIIG---------------IFGVHRQPETFPNPDEFIPERHENGSRVAP---FK 440
            ..|.|:|.|..:..|               |:|        .:.:||.|||........|   ||
plant   388 ENDDVLPDGHRVSKGDNIYYISYAMGRMTYIWG--------QDAEEFKPERWLKDGVFQPESQFK 444

  Fly   441 MIPFSAGPRNCIGQKFAQLEMKMMLAKIVR--EYELLPMGQRVECIVNIVLRSETGFQL 497
            .|.|.||||.|||:.||..:||::...::.  .:::.....:|.....:.|..:.|..|
plant   445 FISFHAGPRICIGKDFAYRQMKIVSMALLHFFRFKMADENSKVSYKKMLTLHVDGGLHL 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	116/482 (24%)
CYP704A1	NP_850427.2	CYP86A	69..501	CDD:410687	114/463 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920