Protein Alignment Cyp4d8 and Cyp4x1

DIOPT Version :9

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001003947.1
• Gene: Cyp4x1 / 81906
• MGIID: 1932403
• Length: 507
• Species: Mus musculus
• Alignment Length: 513
• Identity: 150/513 - (29%)
• Similarity: 262/513 - (51%)
• Gaps: 40/513 - (7%)

  Fly     2 LLFLLVVLLFGAGWIIHLGQADRRRKVANLPGPICPPLIGAMQLMLRLNPKTFIKVGREYVLKFG 66
            |:|.|.::|..| ..::|.:....|.::..|||....|:|..:.:...|.:|..::.:::...|
Mouse    18 LVFCLALVLMQA-MKLYLRRQRLLRDLSPFPGPPAHWLLGHQKFLQEDNMETLDEIVKKHPCAF- 80

  Fly    67 HLQRVWI--FNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNGLLLSDGKVWHQRRKII 129
               ..|:  |.....:. |.:..:..||..:..::: ::::|...:|.|||..||..|.|.|.::
Mouse    81 ---PCWVGPFQAFFYIY-DPDYAKIFLSRTDPKMQY-LHQLLTPCIGRGLLNLDGPRWFQHRCLL 140

  Fly   130 TPTFHFSILEQFVEVFDQQSNICVQRLAQ--KANGNTFDVYRSICAAALDIIAETAMGTKIYAQA 192
            ||.||..||:..|:.......:.:.:..:  .....|.:|:..|....||||.:.|.|.:...|.
Mouse   141 TPAFHQDILKPCVDTMAHSVKVMLDKWEKMWTTQETTIEVFEHINLMTLDIIMKCAFGQETNCQI 205

  Fly   193 N---ESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQTQLIRTMQEFTIKVIEKRR 254
            |   ||  |.:|..|...::|.|..:.:...:::|.|: |.....| :|.:.:.::|.|:|:.|:
Mouse   206 NGTYES--YVKATFELGEIISSRLYNFWHHHDIIFKLS-PKGHCFQ-ELGKVIHQYTEKIIQDRK 266

  Fly   255 QALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTV-DGRPLTNDEIREEVDTFMFEGHDTTTSAL 318
            :.|:: |.|..||....:       .||::|.:.. |.|..::.::|.||:|||:.|||.:.:::
Mouse   267 KILKN-QVKQDDTQTSQI-------FLDIVLSAQAEDERAFSDADLRAEVNTFMWAGHDASAASI 323

  Fly   319 SFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESLRMYPPVPIVGRKL 383
            |:.|:.|:.:||.|.:...||..:||...|  ::...|.|:.|....|||:||:.||||.:.|:|
Mouse   324 SWLLYCLALNPEHQDRCRTEIRSILGDGSS--ITWEQLDEMSYTTMCIKETLRLIPPVPSISREL 386

  Fly   384 QTDFKYT--HSVHGDGVIPAGSEIIIGIFGVHRQPETFPNPDEFIPER--HENGSRVAPFKMIPF 444
            .......  ||      :|||..:::.|:|:|..|..:.:|..|.|.|  .||..:..|...:||
Mouse   387 SKPLTLPDGHS------LPAGMTVVLSIWGLHHNPAVWNDPKVFDPLRFTKENSDQRHPCAFLPF 445

  Fly   445 SAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVECI-VNIVLRSETGFQLGMRK 501
            |:||||||||:||.||:|:.:|.|:..:::.|...|.... .:.|||.:.|..|.::|
Mouse   446 SSGPRNCIGQQFAMLELKVAIALILLHFQVAPDLTRPPAFSSHTVLRPKHGIYLHLKK 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	133/443 (30%)
Cyp4x1	NP_001003947.1	p450	47..499	CDD:278495	141/477 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845095
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750