DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d8 and BAS1

DIOPT Version :9

Sequence 1:	NP_523961.2	Gene:	Cyp4d8 / 38841	FlyBaseID:	FBgn0015033	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_180239.1	Gene:	BAS1 / 817212	AraportID:	AT2G26710	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	540	Identity:	155/540 - (28%)
Similarity:	242/540 - (44%)	Gaps:	82/540 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLLFLLVVLLFGAGWIIHLGQADRRRKV------ANLPGPICPPLIG------AMQLMLRLNPKT 53
            ::|.|::|......|.       |.||:      ..:.||.....||      .|.|....:|..
plant    18 VILSLVIVKGMSLLWW-------RPRKIEEHFSKQGIRGPPYHFFIGNVKELVGMMLKASSHPMP 75

  Fly    54 FIKVGREYVLKFGHLQR--------VWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWL 110
            |.......||.|.|..|        ||......:...|.:|..::.|..|...|:..:.::.|..
plant    76 FSHNILPRVLSFYHHWRKIYGATFLVWFGPTFRLTVADPDLIREIFSKSEFYEKNEAHPLVKQLE 140

  Fly   111 GNGLLLSDGKVWHQRRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKANGN---TFDVYRSIC 172
            |:|||...|:.|...||||:||||...|:..|.|..:.....|.:.:.|.:.|   ..|||....
plant   141 GDGLLSLKGEKWAHHRKIISPTFHMENLKLLVPVVLKSVTDMVDKWSDKLSENGEVEVDVYEWFQ 205

  Fly   173 AAALDIIAETAMGTK-------IYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPH 230
            ....|:|:.||.|:.       ...||.:....|||           |..|::.....|. |..:
plant   206 ILTEDVISRTAFGSSYEDGRAVFRLQAQQMLLCAEA-----------FQKVFIPGYRFFP-TRGN 258

  Fly   231 LK-WRQTQLIRTMQEFTIKVIEKRRQ-ALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTVDGRP 293
            || |:   |.:.:::..:|:||:||| |::.:..:..:.|.:|            ||...:..:.
plant   259 LKSWK---LDKEIRKSLLKLIERRRQNAIDGEGEECKEPAAKD------------LLGLMIQAKN 308

  Fly   294 LTNDEIREEVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRD-LG 357
            :|..:|.||..:|.|.|..||::.|::....||.|||.|||..:|:::|.|   ||.|..:| :.
plant   309 VTVQDIVEECKSFFFAGKQTTSNLLTWTTILLSMHPEWQAKARDEVLRVCG---SRDVPTKDHVV 370

  Fly   358 ELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETFPNP 422
            :||.:..::.||||:|||:....|:.::|.|.     |...||.|:|::|.|..||.....:.|.
plant   371 KLKTLSMILNESLRLYPPIVATIRRAKSDVKL-----GGYKIPCGTELLIPIIAVHHDQAIWGND 430

  Fly   423 -DEFIPERHENG-SRVA--PFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVRE--YELLPMGQRV 481
             :||.|.|..:| .|.|  |...|||..|.|.||||..|.|:.|:.||.:::.  :.|.|..|..
plant   431 VNEFNPARFADGVPRAAKHPVGFIPFGLGVRTCIGQNLAILQAKLTLAVMIQRFTFHLAPTYQHA 495

  Fly   482 ECIVNIVLRSETGFQLGMRK 501
            ..:: ::|..:.|..:..|:
plant   496 PTVL-MLLYPQHGAPITFRR 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	136/457 (30%)
BAS1	NP_180239.1	CYP734	85..509	CDD:410732	138/459 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.860