DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d8 and CYP96A5

DIOPT Version :9

Sequence 1:	NP_523961.2	Gene:	Cyp4d8 / 38841	FlyBaseID:	FBgn0015033	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_179782.1	Gene:	CYP96A5 / 816727	AraportID:	AT2G21910	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	557	Identity:	124/557 - (22%)
Similarity:	236/557 - (42%)	Gaps:	116/557 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LFLLVVLLFGAGWIIHLGQADRRRKVANLPGPICPPLIGAMQLMLRLNPKTFIKVGREYVLKFGH 67
            :|:.:::.|...::||    .:..::.....|:...|.|.:.::.|:|         :||.:...
plant     9 VFIALLVFFFFHFLIH----KKSHQITPRNWPVLGMLPGVLVMLHRIN---------DYVAEILE 60

  Fly    68 LQRV-------WIFNRLLIMSGDAELNEQLLSSQ-EHLVKHPVYKVLGQWLGNGLLLSDGKVWHQ 124
            :..:       |.....::::.|....:.:.||. .:..|.|.:|.:..:||||:..:|.|:|..
plant    61 VSNLTFAFKGPWFSGMNMLITADPSNIQHVFSSNFSNYDKGPEFKEMFDFLGNGIFTADSKLWED 125

  Fly   125 RRK-IITPTFH-----FS--------------ILEQFVE---VFDQQSNICVQRLAQKANGNTFD 166
            .|| .:....|     ||              :|:.|.|   |||.|.  ..||||       ||
plant   126 MRKSALVVLSHQGFQSFSLRTITCKIKNGLVPVLDHFAEANTVFDLQD--VFQRLA-------FD 181

  Fly   167 VYRSICAAALDIIAETAMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHL 231
            |..::....      .:....|....||   ||:|:::...::.:|.:.             |.:
plant   182 VTLTLVTGC------DSSSLSIEMPKNE---YAKAMDDAEEVVVYRHVK-------------PVV 224

  Fly   232 KWRQTQLIRTMQEFTIKVIEKRRQALEDQQSKLMDTADEDV--------GSKRRMALLDVLLMST 288
            .|:....|...:|   |.:::...|.:...:|.:....|::        |......||.|.:...
plant   225 LWKLQNWIGLGEE---KKMKEANAAFDRSCAKYISAKREEIISHHSNIGGEAHAEDLLSVYMNLD 286

  Fly   289 VDGRPLTNDE----IREEVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEI-VQVLGTDRS 348
            :....|.|..    :::.:.:||..|.|...:.|::....||::||...|:.:|| ..:.|:..|
plant   287 ISKYELLNPNDDNFLKDIIKSFMLAGRDAIATTLTWFFWLLSKNPEAVTKIRQEINTNLPGSGMS 351

  Fly   349 RPVSIRDLGELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDGVIPAGS------EIII 407
              :....|.::.|:...:.||||:|.|:|.   :.:|..|       ..|:|:|.      :|:.
plant   352 --LDADKLNKMVYLHGALCESLRLYAPIPF---ERKTPIK-------QDVLPSGHMVDKNWKILF 404

  Fly   408 GIFGVHRQPETF-PNPDEFIPER----HENGSRVAP-FKMIPFSAGPRNCIGQKFAQLEMKMMLA 466
            .::.:.|....: .:..||.|||    ...|.:..| ||...|::|||||:|:..:.|:||.:..
plant   405 SVYALGRMRSVWGQDASEFKPERWISERNGGLKHEPSFKFFVFNSGPRNCLGKNLSFLQMKTVAV 469

  Fly   467 KIVREYEL-LPMGQRVECIVNIVLRSETGFQLGMRKR 502
            :|:|.|:: :..|.::|...:|:|..:.|.::.:.||
plant   470 EIIRNYDIKVVEGHKIEPASSIILHMKHGLKVTVSKR 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	111/487 (23%)
CYP96A5	NP_179782.1	p450	1..506	CDD:299894	122/555 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920