Protein Alignment Cyp4d8 and cyp4v2.2

DIOPT Version :9

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001072667.1
• Gene: cyp4v2.2 / 780124
• XenbaseID: XB-GENE-977085
• Length: 523
• Species: Xenopus tropicalis
• Alignment Length: 518
• Identity: 209/518 - (40%)
• Similarity: 309/518 - (59%)
• Gaps: 32/518 - (6%)

  Fly     1 MLLFLLVVLLFGAGWIIHLGQADRRRKVAN-LPGPICP--PLIGAMQLMLRLNPKTFIKVGREYV 62
            :||.||.:.:..|     |....|:|::.. :||| .|  ||||. .|.|:.|...|.....||.
 Frog    18 VLLTLLALSILPA-----LQDYVRKRRILKPIPGP-GPNYPLIGD-ALFLKNNGGDFFLQICEYT 75

  Fly    63 --LKFGHLQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNGLLLSDGKVWHQR 125
              .:...|.:|||.....|:...|:..|.:|||.:|:.|..:||.|..|||.|||.|.|:.|..|
 Frog    76 ESYRLQPLLKVWIGTIPFIVVYHADTVEPVLSSSKHMDKAFLYKFLHPWLGKGLLTSTGEKWRSR 140

  Fly   126 RKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKANGNTFDVYRSICAAALDIIAETAMGTKIYA 190
            ||:|||||||:||.:|:||.::||.|.|::|....:|.:||.:..:...|||||:|||||.||.|
 Frog   141 RKMITPTFHFAILSEFLEVMNEQSKILVEKLQTHVDGESFDCFMDVTLCALDIISETAMGRKIQA 205

  Fly   191 QANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLK--WRQTQLIRTMQEFTIKVIEKR 253
            |:|..:.|.:|:.:.:.::..|....:|.::.|:.    ||:  ....:.::.:..||.|.|.:|
 Frog   206 QSNRDSEYVQAIYKMSDIIQRRQKMPWLWLDFLYA----HLRDGKEHDKNLKILHSFTDKAILER 266

  Fly   254 RQALE---DQQSKLMDTADEDVGSKRRMALLDVLLMSTVD-GRPLTNDEIREEVDTFMFEGHDTT 314
            .:.|:   :|:.:..|:..|....|:|.|.||:|||:|.| |..::..:||||||||||||||||
 Frog   267 AEELKKMGEQKKEHCDSDPESDKPKKRSAFLDMLLMATDDAGNKMSYMDIREEVDTFMFEGHDTT 331

  Fly   315 TSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESLRMYPPVPIV 379
            .:||::.|..|..|||.|.::.:|:.:|.|.. .|||::.||.:|:|:|.|||||||:||.||:.
 Frog   332 AAALNWSLFLLGSHPEAQRQVHKELDEVFGKS-DRPVTMDDLKKLRYLEAVIKESLRIYPSVPLF 395

  Fly   380 GRKLQTDFKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETFPNPDEFIPERH--ENGSRVAPFKMI 442
            ||.:..|.    |:.|..| |.|..::|..:.:||.||.||.|:||.|||.  ||.|...|:..|
 Frog   396 GRTVTEDC----SIRGFHV-PKGVNVVIIPYALHRDPEYFPEPEEFRPERFFPENASGRNPYAYI 455

  Fly   443 PFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVE-CIV-NIVLRSETGFQLGMRKRK 503
            |||||.||||||:||.:|.|::|:.|:|.|.:....:|.| |:: .::||.:.|..:.::.|:
 Frog   456 PFSAGLRNCIGQRFALMEEKVVLSSILRNYWVEASQKREELCLLGELILRPQDGMWIKLKNRE 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	186/440 (42%)
cyp4v2.2	NP_001072667.1	p450	45..509	CDD:365848	199/475 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010