DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d8 and Cyp4f37

DIOPT Version :9

Sequence 1:	NP_523961.2	Gene:	Cyp4d8 / 38841	FlyBaseID:	FBgn0015033	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	XP_038935973.1	Gene:	Cyp4f37 / 691312	RGDID:	1585102	Length:	526	Species:	Rattus norvegicus

Alignment Length:	418	Identity:	143/418 - (34%)
Similarity:	223/418 - (53%)	Gaps:	40/418 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 KHPVY-KVLGQWLGNGLLLSDGKVWHQRRKIITPTFHFSILEQFVEVFDQQSNI--------CVQ 154
            |.|.: ..|..|||:||.||.|..|.:.|:::||.|||.||:.:|:.|:|..||        |::
  Rat   120 KDPTFLHFLKPWLGDGLFLSSGDKWSRHRRLLTPAFHFDILKPYVKTFNQSVNIMHAKWKHLCLE 184

  Fly   155 RLAQKANGNTFDVYRSICAAALDIIAETAMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQ 219
            ..|:      .:::.:|....||.:.:...|.....|.:.| .|..|..|.::|...|...::|.
  Rat   185 GSAR------LEMFENISLMTLDSLQKCLFGFDSNCQESPS-EYISATLELSSLTRKRSYKLFLY 242

  Fly   220 VELLFTLTHPHLKWRQT-QLIRTMQEFTIKVIEKRRQALEDQQSKLMDTADEDVGSK-----RRM 278
            ::.|:..|....::|:. .|:.:   ||..||.:||:.|..|      ..||.:.||     :.:
  Rat   243 LDFLYYRTADGQRFRKACDLVHS---FTDAVIRERRRLLSSQ------GVDEFLESKTKSKSKTL 298

  Fly   279 ALLDVLLMSTVD-GRPLTNDEIREEVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQV 342
            ..:||||::..: |:.|::::||.|.|||||.|||||.||||:.|:.|:.|||.|.:..:|:.::
  Rat   299 DFIDVLLLAKDEHGKELSDEDIRAEADTFMFGGHDTTASALSWILYNLASHPEYQERCRQEVWEL 363

  Fly   343 LGTDRSRPVSIRDLGELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDG-VIPAGSEII 406
            |.......:...||.:|.::...||||||::||...:.|:...|.     |..|| |||.|:..:
  Rat   364 LRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPAVDLLRRCTQDI-----VLPDGRVIPKGNICV 423

  Fly   407 IGIFGVHRQPETFPNPDEFIPERH--ENGSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIV 469
            |.|||:|..|..:|:|:.:.|.|.  ||..:.:|...|||||||||||||.||..|:|:.:...:
  Rat   424 ISIFGIHHNPSVWPDPEVYDPFRFDPENRQKRSPLSFIPFSAGPRNCIGQTFAMNEVKVAVGLTL 488

  Fly   470 REYELLPMGQRVECIVNIVLRSETGFQL 497
            ..:..||..:.......::||:|.|..|
  Rat   489 LRFRFLPDDKEPRRKPELILRAEGGLWL 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	142/416 (34%)
Cyp4f37	XP_038935973.1	CYP4F	74..517	CDD:410772	143/418 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348564
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750