Protein Alignment Cyp4d8 and Cyp4f37

DIOPT Version :9

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001093657.1
• Gene: Cyp4f37 / 677156
• MGIID: 3780112
• Length: 546
• Species: Mus musculus
• Alignment Length: 509
• Identity: 160/509 - (31%)
• Similarity: 248/509 - (48%)
• Gaps: 79/509 - (15%)

  Fly    15 WII-HLGQADRRRKVANLP---------------GPICPPLIGAMQLMLRLNPKTFIKVGREYVL 63
            |.: |||..:...:...|.               ||:.|        :||:....|:.
Mouse    59 WFLGHLGMIEHNEEGMQLMTEAGQTYRDVHLCWLGPVIP--------VLRIVDPAFVA------- 108

  Fly    64 KFGHLQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNGLLLSDGKVWHQRRKI 128
                        .||:.|.        |.:.:....|...|   .|||:||.|:.|..|.:.|::
Mouse   109 ------------PLLLASA--------LVAPKDTTFHTFVK---PWLGDGLFLNSGDKWSRHRRL 150

  Fly   129 ITPTFHFSILEQFVEVFDQQSNIC---VQRLAQKANGNTFDVYRSICAAALDIIAETAMGTKIYA 190
            :||.|||.||:.:|::|:|..||.   .:.|:.:.:.. .:::..|....||.:.:...|.....
Mouse   151 LTPAFHFDILKPYVKIFNQSVNIMHAKWKHLSSEGSAR-LEMFEHISLMTLDSLQKCLFGFDSNC 214

  Fly   191 QANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQTQLIRTMQEFTIKVIEKRRQ 255
            |.:.| .|..|:.|.::|:..|...::|.|:.|:..|....::|:.  ...:..||..||.:||.
Mouse   215 QESPS-EYISAILELSSLVIKRSHQLFLFVDFLYYHTADGRRFRKA--CDLVHNFTDAVIRERRH 276

  Fly   256 ALEDQQSKLMDTADEDVGSK---RRMALLDVLLMSTVD-GRPLTNDEIREEVDTFMFEGHDTTTS 316
            .|..|..      ||.:.||   :.:..:||||::..: |:.|::::||.|.|||||.|||||.|
Mouse   277 TLSSQNH------DEFLKSKTKSKTLDFIDVLLLAKDEHGKELSDEDIRAEADTFMFGGHDTTAS 335

  Fly   317 ALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESLRMYPPVPIVGR 381
            |||:.|:.|:||||.|.:..:|:.::|.....:.:...||.:|.::...||||||::|||..:.|
Mouse   336 ALSWILYNLARHPEYQERCRQEVQELLRGREPQEIEWDDLAQLPFLTMCIKESLRLHPPVIDLLR 400

  Fly   382 KLQTDFKYTHSVHGDG-VIPAGSEIIIGIFGVHRQPETFPNPDEFIPERH--ENGSRVAPFKMIP 443
            :...|.     |..|| |||.|:..:|.|||:|..|..:|:|:.:.|.|.  ||..:..|...||
Mouse   401 RCTRDI-----VLPDGRVIPKGNICVISIFGIHHNPSVWPDPEVYDPFRFDPENAHKRPPLAFIP 460

  Fly   444 FSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVECIVNIVLRSETGFQL 497
            |||||||||||.||..||.:.||..:..:.:||..:.......|:||:|.|..|
Mouse   461 FSAGPRNCIGQTFAMNEMMVALALTLLRFRILPDDKEPRRKPEIILRAEGGLWL 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	148/440 (34%)
Cyp4f37	NP_001093657.1	CYP4F	74..515	CDD:410772	156/494 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845168
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2429
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.770