Protein Alignment Cyp4d8 and Cyp4a31

DIOPT Version :10

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_964002.2
• Gene: Cyp4a31 / 666168
• MGIID: 3028580
• Length: 509
• Species: Mus musculus
• Alignment Length: 523
• Identity: 158/523 - (30%)
• Similarity: 258/523 - (49%)
• Gaps: 90/523 - (17%)

  Fly    39 LIGAMQ------LMLRLNPKTFIKVGREYVLK-------------FGHLQRVWIFNRLLIMSGDA 84
            |.|.:|      |:|.|.....:.:.|:::||             |||.|          ..||.
Mouse    15 LSGFLQVASVFCLLLLLVKAVQVYLHRKWLLKALQQFPSPPFHWFFGHEQ----------FKGDQ 69

  Fly    85 ELNEQLLSSQEHL----------------VKHP----------------VYKVLGQWLGNGLLLS 117
            ||.| ::|..|:.                |..|                .|::|..|:|.||||.
Mouse    70 ELQE-IVSCIENFPSAFPRWFWGSKAYLTVYDPDYMKVILGRSDPKANGAYRLLAPWIGYGLLLL 133

  Fly   118 DGKVWHQRRKIITPTFHFSILEQFVEVFDQQSNICV---QRLAQKANGNTFDVYRSICAAALDII 179
            :|:.|.|.||::||.||:.||:.:|:.......:.:   :|||  ...::.::::.|....||.:
Mouse   134 NGQSWFQHRKMLTPAFHYDILKTYVKNMADSIRLMLDKWERLA--GQDSSIEIFQHISLMTLDTV 196

  Fly   180 AETAMGTK--IYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTL-THPHLKWRQTQLIRT 241
            .:.|...|  :....|..| |.:|:.:...|:..|..:::.|.:.::.| ::..|..:..||
Mouse   197 MKCAFSHKGSVQVDGNYKT-YLQAIGDLNNLVHSRVRNMFHQNDTIYKLSSNGRLSNQACQL--- 257

  Fly   242 MQEFTIKVIEKRRQALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTVDGRPLTND-EIREEVDT 305
            ..:.|..||:.|:..|:|:...      |::..|||:..||:||.:.::.....:| ::|.||||
Mouse   258 AHDHTDGVIKMRKDQLQDEGEL------ENIKKKRRLDFLDILLFARMENEDSMSDKDLRAEVDT 316

  Fly   306 FMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESL 370
            ||.||||||.|.:|:..:.|:.|||.|.:..||:..:||...|  ::...|.::.|....|||:|
Mouse   317 FMIEGHDTTASGVSWIFYALATHPEHQQRCREEVQSLLGDGSS--ITWDHLDQIPYTTMCIKEAL 379

  Fly   371 RMYPPVPIVGRKLQTDFKYTHSVHGDGV-IPAGSEIIIGIFGVHRQPETFPNPDEFIPERHENGS 434
            |:|||||.:||:|.|...:.     ||. :|.|.::.:.|:|:|..|:.:|||:.|.|.|....|
Mouse   380 RLYPPVPSIGRELSTSVTFP-----DGCSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDS 439

  Fly   435 RVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVE-CIVNIVLRSETGFQLG 498
            .......:|||.|.|||||::||..|:|:::|..:..:||||...||. .:...||:|:.|..|.
Mouse   440 PRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLPDPTRVPMSLARFVLKSKNGIYLH 504

  Fly   499 MRK 501
            ::|
Mouse   505 LKK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	146/471 (31%)
Cyp4a31	NP_964002.2	CYP4B-like	71..504	CDD:410771	140/452 (31%)