Protein Alignment Cyp4d8 and Cyp3a57

DIOPT Version :9

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001093650.1
• Gene: Cyp3a57 / 622127
• MGIID: 3646373
• Length: 503
• Species: Mus musculus
• Alignment Length: 500
• Identity: 132/500 - (26%)
• Similarity: 242/500 - (48%)
• Gaps: 76/500 - (15%)

  Fly     2 LLFLLVVLLFGAGWIIHLGQADRRRKVANLPGPICPPLIG----AMQLMLRLNPKTFIKVGREYV 62
            |:|..:...:..|....||          :|||...||.|    .:..|.:.:...:.|.|
Mouse    19 LVFFYIYGTYSHGLFKKLG----------IPGPKPLPLFGNIINYLDGMWKFDDDCYKKYG---- 69

  Fly    63 LKFGHLQRVWIFNR-----LLIMSGDAELNEQLLSSQEHLV---KHPVYKVLGQWLGNGLLLSDG 119
                   ::|.|..     |.||  |.|:.:.:|..:.:.|   :.|...|  .:|...:.:|:.
Mouse    70 -------KIWGFYEGPQPILAIM--DPEIIKIVLVKECYSVFTNRRPFGPV--GFLKKSITISED 123

  Fly   120 KVWHQRRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKANG----NTFDVYRSICAAALDIIA 180
            :.|.:.|.:::|||..|.|::...:..|..:|.|:.|.::...    |..|::.   |.::|:|.
Mouse   124 EEWKRLRTLLSPTFTSSKLKEMFPIMRQYGDILVRNLRREEEKEEPINMKDIFG---AYSMDVIT 185

  Fly   181 ETAMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQTQLI-RTMQE 244
            .|:.|..|.:..|...|:.:.:.:   :|.::|...:|...:||....|..:.....:. |....
Mouse   186 GTSCGVNIDSLNNPQDPFVQKIKK---ILKFKFFDPFLLSVVLFPFLTPIYEMLNLSIFPRQSMN 247

  Fly   245 FTIKVIEKRRQALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTVDG------RPLTNDEIREEV 303
            |..|.::|.:      :.:|      |...|.|:..|. |:|:|.:.      :.|::.|:..:.
Mouse   248 FFKKFVKKMK------KDRL------DYNQKNRVDFLQ-LMMNTQNSKGQESLKALSDLEMAAQT 299

  Fly   304 DTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKE 368
            ..|:|.|:|.|::::||.::||:.||:||.|:.:||.:.|  ....||:...|.:::|::.|:.|
Mouse   300 LIFIFGGYDGTSTSISFIMYELATHPDVQKKLQDEIDRAL--PNKAPVTYDALMDMEYLDMVVNE 362

  Fly   369 SLRMYPPVPIVGRKLQTDFKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETFPNPDEFIPER--HE 431
            |||:||.|..:.|..:.|.:    :|| ..||.|:.::|.|:.:||.||.:|.|::|.|||  .|
Mouse   363 SLRLYPVVSRIDRFSKKDVE----IHG-VFIPKGTIVMIPIYPLHRDPEYWPEPEDFCPERFSKE 422

  Fly   432 NGSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLP 476
            |...:.|:..:||..|||||||.:||.:.:|:.:..:::.:.:.|
Mouse   423 NKGNIDPYIYMPFGNGPRNCIGMRFALISVKLAVTGVLQNFTVQP 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	117/431 (27%)
Cyp3a57	NP_001093650.1	p450	39..493	CDD:278495	126/469 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910