Protein Alignment Cyp4d8 and cyp46a1.3

DIOPT Version :9

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001027517.1
• Gene: cyp46a1.3 / 613109
• XenbaseID: XB-GENE-969052
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 540
• Identity: 148/540 - (27%)
• Similarity: 263/540 - (48%)
• Gaps: 96/540 - (17%)

  Fly     1 MLLFLLVVLLFGAGWI--IHLGQADRRRKVANLPGPICPP----LIGAMQLMLRLNPKTFIKVGR 59
            :|..:|:..|..:|:|  ||:       |..::||   ||    .:|....||||.....:....
 Frog    14 LLALILICFLLFSGYIHYIHM-------KYDHIPG---PPRDSFFLGHSPTMLRLMKNNLLMYDH 68

  Fly    60 --EYVLKFGHLQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLG-----QWLGNGLLLS 117
              .:|.|:|.:.|:...:|::|:....|..::||.|.:: .|...|.|:.     :::|.||:..
 Frog    69 FLGWVQKYGPVVRINGLHRVIILVVSPEAVKELLMSPKY-SKDKFYDVIANMFGVRFMGKGLVTD 132

  Fly   118 -DGKVWHQRRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKANGN-TFDVYRSICAAALDIIA 180
             |...||::|:|:.|.|..:.|...:..|::::...:::|.:||:|. ...::..:....||:|.
 Frog   133 RDYDHWHKQRRIMDPAFSRTYLMGLMGPFNEKAEELMEKLMEKADGKCEIKMHDMLSRLTLDVIG 197

  Fly   181 ETAMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQTQ--LIRTMQ 243
            :.|.|.::.:..::.||:.:|::              |.::.:..:.:|.:::...:  .||.:|
 Frog   198 KVAFGMELNSLNDDLTPFPKAIS--------------LVMKGIVEMRNPMVRYSLAKRGFIRKVQ 248

  Fly   244 EFTIKVIEKR-RQALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTVDGRPLTNDEIREEVD--- 304
            | :|:::.:. ::.:|.:|.::.|..:..|         |:|.      :.|....:.||.|
 Frog   249 E-SIRLLRQTGKECIERRQKQIQDGEEIPV---------DILT------QILKGAAMEEECDPEI 297

  Fly   305 ------TFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYME 363
                  ||...|.:||.:.|||.:.||.|:||:..|...||.:|:|:  .|.:...|||:|:|:.
 Frog   298 LLDNFVTFFIAGQETTANQLSFVVMELGRNPEILEKAQAEIDEVIGS--KRDIEYEDLGKLQYLS 360

  Fly   364 CVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDGV-IPAGSEIIIGIFGVHR------QPETFPN 421
            .|:||:||:||..|...|.|..|...      ||| :|....|::..:.:.|      .|.|| |
 Frog   361 QVLKETLRLYPTAPGTSRGLTEDMVI------DGVKVPENVTIMLNSYIMGRMEQYYSDPLTF-N 418

  Fly   422 PDEFIPERHENGSRVAP---FKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYEL-LPMGQRVE 482
            ||.|.|:        ||   :...|||.|||:||||.|:|:|.|:::||:::.||. |..||..:
 Frog   419 PDRFSPD--------APKPYYSYFPFSLGPRSCIGQVFSQMEAKVVMAKLLQRYEFELAEGQSFK 475

  Fly   483 CIVNIVLRSETGFQLGMRKR 502
            .:....||...|....:|.|
 Frog   476 ILDTGTLRPLDGVICRLRPR 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	127/460 (28%)
cyp46a1.3	NP_001027517.1	p450	40..491	CDD:306555	138/501 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910