Protein Alignment Cyp4d8 and LOC4577452

DIOPT Version :10

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: XP_001230597.4
• Gene: LOC4577452 / 4577452
• VectorBaseID: AGAMI1_012198
• Length: 513
• Species: Anopheles gambiae
• Alignment Length: 527
• Identity: 137/527 - (25%)
• Similarity: 244/527 - (46%)
• Gaps: 102/527 - (19%)

  Fly     5 LLVVLLFGAGWI-IHLGQADRRRKVANLP--GPICPPLIGAMQLMLRLNPKTFIKVGREY----- 61
            ::.:||.|.|.: ::|....:.:....:|  .|:.|.....::...:.:.:.|..:.|.|
Mosquito     1 MITLLLLGFGALSLYLYCKIKFKFAEKIPCVEPLHPIFGNGLEFAQKNSYEIFKSLTRAYKDNKR 65

  Fly    62 --VLKFGHLQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNGLLLSDGKVWHQ 124
              .|.||.:.        :|.....:|.:::::.|..:.|..||..:.  :.:|||.:....|..
Mosquito    66 IFKLCFGPIP--------VICPTHPDLIQKIMTEQASMDKPFVYDFMR--VDHGLLTAQYDEWRV 120

  Fly   125 RRKIITPTFHFSILEQFVEVFDQQSNICVQRL---AQKANGNTFDV----YRSICAAALDIIAET 182
            .||.:.|||:..||..|:.:|..    ||.::   .:|..|:...:    :.|.|  .|::|..|
Mosquito   121 HRKALNPTFNTRILNSFIPIFTD----CVAKMIANMEKHAGDEKPINVLEFTSPC--TLEMICRT 179

  Fly   183 AMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQTQLIRTMQE--- 244
            ::|.|:..:..:. .:.|.:......:..|..:..|         :|.:.:|.|:..:...:
Mosquito   180 SLGGKVLEREGKQ-EFIEGLEIILHNVGLRMFNANL---------YPDIVYRNTRFYKAEMDARK 234

  Fly   245 ----FTIKVIEKRRQALEDQQSKLMD------TADED------------VGSKRRMALLDVLLMS 287
                ||.|||.::|...|::....:|      ||||:            :..|:....:|.||..
Mosquito   235 ICYAFTDKVIREKRAKFEEKLRNAVDSNNNSTTADENGNVVFADEEDDMLSYKKPQIFVDQLLTI 299

  Fly   288 TVDGRPLTNDEIREEVDTFMFEGHDTT-TSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPV 351
            ..||:|.|::||.:.:.|.:..|::|: |.|...|| .|:.|||:|.:...||.::|..|..  .
Mosquito   300 PNDGKPFTHEEITDHIYTMIAAGNETSATQAAHACL-LLAMHPEIQDRAAAEICELLADDVE--Y 361

  Fly   352 SIRDLGELKYMECVIKESLRMYPPVPIVGRK----LQTDFKYTHSVHGDGVIPAGSEIIIGIFGV 412
            :...|.:::|:|.|||||.|:.|...:.|||    :|.|         :.|||.|..:::.:|.:
Mosquito   362 THETLKQMQYLERVIKESQRLCPVAAVYGRKTIGTIQLD---------EYVIPKGFILLLNVFAL 417

  Fly   413 HRQPETF-PN-----PDEFIPE----RHENGSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAK 467
            |||.|.: ||     ||.|:||    ||       |:..:|||.|||.|||.::|.:.:|::|::
Mosquito   418 HRQKEFWGPNADKFDPDHFLPERVKARH-------PYAYLPFSGGPRGCIGSRYAMMSLKIILSQ 475

  Fly   468 IVREYEL 474
            |::.|.|
Mosquito   476 ILKNYRL 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	124/456 (27%)
LOC4577452	XP_001230597.4	None