Protein Alignment Cyp4d8 and Cyp4a30b

DIOPT Version :10

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: XP_006503285.1
• Gene: Cyp4a30b / 435802
• MGIID: 3717145
• Length: 510
• Species: Mus musculus
• Alignment Length: 538
• Identity: 156/538 - (28%)
• Similarity: 263/538 - (48%)
• Gaps: 87/538 - (16%)

  Fly     2 LLFLLVVLLFGAGWIIHLGQADRRRKVANL----PGPICPP--LIG-------AMQLMLRLN--P 51
            ||.||::||..|.:.:|     |:..:.:|    |.|  ||  |.|       ..|::|.:.  |
Mouse    24 LLGLLLLLLKSAQYYLH-----RQWLIKSLQQFPPAP--PPQWLFGNTLKDQDLQQILLCVEKFP 81

  Fly    52 KTFIKVGREYVLKFGHLQRVWIF-NRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNGLL 115
            .|:::               |:: |...::..|.:..:.:|...:..|... |.....|:|.|||
Mouse    82 STYVR---------------WLWGNHARVVIYDPDYMKVILGRSDPKVVRS-YSFFAPWIGYGLL 130

  Fly   116 LSDGKVWHQRRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKANGN-TFDVYRSICAAALDII 179
            |.:||.|.|.|:::||.||:.||:.:|.:.....::.:.:..|..:.: ..::|:.|....::.:
Mouse   131 LLNGKKWFQHRRMLTPAFHYDILKPYVGIMVDSVHVMLDKWEQLVDQDCPLEIYQDISLMTMETM 195

  Fly   180 AETA---MGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLT-------------H 228
            .:.|   .|:........|..|.:||.:.|.|:..|..:.:.|...:::|:             |
Mouse   196 MKCAFSYQGSVQLEDCRNSKSYIKAVEDLTHLIYLRVRNGFHQNNTIYSLSSNGRSFYHACQIAH 260

  Fly   229 PHLKWRQTQLIRTMQEFTIKVIEKRRQALEDQQSKLMDTADEDVGSKRRMALLDVLLMS-TVDGR 292
            .|               |.:||..|:..|:::...      |....|:|:..||:||.: |.||:
Mouse   261 KH---------------TERVIRMRKAQLQNEAEL------EKFRKKKRLDFLDILLFAQTEDGK 304

  Fly   293 PLTNDEIREEVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLG 357
            .|:::::|.|:||||||||:||.|.:|:..:.|:.|||.|.:..||:..:||...|  |::..|.
Mouse   305 SLSDEDVRAEMDTFMFEGHNTTASGISWIFYALATHPEHQQRCREEVKSILGNGTS--VTLNHLD 367

  Fly   358 ELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDGV-IPAGSEIIIGIFGVHRQPETFPN 421
            ::.|....|||:||:|||:|...|:|.:...:.     ||. :|.|..:.:..:|:|..|...||
Mouse   368 QMPYTTMCIKEALRLYPPIPGASRELSSPVTFP-----DGCSLPKGFLVTLSFYGLHHNPRLRPN 427

  Fly   422 PDEFIPERHENGSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVECIVN 486
            .:.|.|.|...|:.......:|||||.|||||::|...|:|:.:|..:..:||||...||..:|:
Mouse   428 AEVFDPSRFAPGAPRQTHAFLPFSAGTRNCIGKQFTMNELKVAVALTLLRFELLPDPTRVPILVS 492

  Fly   487 -IVLRSETGFQLGMRKRK 503
             |||:|:.|..|..:|.|
Mouse   493 KIVLKSKNGIYLHTKKLK 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	133/451 (29%)
Cyp4a30b	XP_006503285.1	CYP4B-like	70..505	CDD:410771	137/478 (29%)