Protein Alignment Cyp4d8 and Cyp12b2

DIOPT Version :10

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 471
• Identity: 103/471 - (21%)
• Similarity: 181/471 - (38%)
• Gaps: 92/471 - (19%)

  Fly    37 PPLIGAMQLMLRLNPKTFIKVGREYVLKFGHLQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHP 101
            |.::|....:...||..|....|.        :.||          ...:..:.|:....:.:..
  Fly    97 PGMMGKPNAVFTYNPDDFEMTYRN--------EGVW----------PIRIGLESLNYYRKIHRPD 143

  Fly   102 VYKVLGQWLGNGLLLSDGKVWHQRRKIITPT-FHFSILEQFVEVFDQQSNICVQRLAQKANGNTF 165
            |:|.:|     ||....|:.|...|..:.|. .....:.|.:...||.|...:.:|..:.|..|.
  Fly   144 VFKGVG-----GLASDQGQEWADIRNKVNPVLMKVQNVRQNLPQLDQISKEFIDKLETQRNPETH 203

  Fly   166 ----DVYRSICAAALDIIAETAMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTL 226
                |.:..:...|.:.|:..|:.|::...::...|.|:.:.        :.|..:......|.:
  Fly   204 TLTTDFHNQLKMWAFESISFVALNTRMGLLSDNPDPNADRLA--------KHMRDFFNYSFQFDV 260

  Fly   227 THPHLKWRQTQLIRTMQEFTIKVIEKRRQALEDQQSKLMDTADEDVGSK---RRMALLDVLLMST 288
                    |..:....:....|...|....:.|..|..::||....|..   :...:|:.||
  Fly   261 --------QPSIWTFYKTAGFKKFLKTYDNITDITSNYIETAMRGFGKNDDGKTKCVLEQLL--- 314

  Fly   289 VDGRPLTNDEIREEVDTFM-----FEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRS 348
                     |..::|...|     ..|.|||:||....|:.|:|:|..|.|:..|::::|.|.:.
  Fly   315 ---------EHNKKVAVTMVMDMLMAGIDTTSSACLTILYHLARNPSKQEKLRRELLRILPTTKD 370

  Fly   349 RPVSIRDLG--ELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHS--VHGDGVIPAGSEIIIGI 409
               |:.|..  .:.|:...|||.||:....|       .:|:.|..  |.....:|.|:.:::|:
  Fly   371 ---SLTDQNTKNMPYLRACIKEGLRITSITP-------GNFRITPKDLVLSGYQVPRGTGVLMGV 425

  Fly   410 FGVHRQPETFPNPDEFIPERHENGSRVA------------PFKMIPFSAGPRNCIGQKFAQLEMK 462
            ..:....:.|....||||||........            ||..:||..|||.|||::.|:||::
  Fly   426 LELSNDDKYFAQSSEFIPERWLKSDLAPDIQACPAARTRNPFVYLPFGFGPRTCIGKRIAELEIE 490

  Fly   463 MMLAKIVREYEL--LP 476
            .:|.:::|.|::  ||
  Fly   491 TLLVRLLRSYKVSWLP 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	97/442 (22%)
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	103/471 (22%)