Protein Alignment Cyp4d8 and Cyp6a21

DIOPT Version :10

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0288232
• Length: 504
• Species: Drosophila melanogaster
• Alignment Length: 550
• Identity: 124/550 - (22%)
• Similarity: 227/550 - (41%)
• Gaps: 114/550 - (20%)

  Fly     5 LLVVLLFGAGWIIHLGQADRRRKVANLPGPICPP--LIGAMQLMLRLNPKTFIKVGREYVLKF-- 65
            ||..||...|::: :......|...:|..|...|  |:|:|:.:  ...::|.::...|..||
  Fly     7 LLTALLALVGYLL-MKWRSTMRHWQDLGIPCEEPHILMGSMKGV--RTARSFNEIWTSYYNKFRG 68

  Fly    66 -GHLQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNG-------------LLL 116
             |.....:.|.|..:...:..|.:|:|           .|...::...|             |.|
  Fly    69 SGPFAGFYWFRRPAVFVLETSLAKQIL-----------IKEFNKFTDRGFFHNPEDDPLSGQLFL 122

  Fly   117 SDGKVWHQRRKIITPTFH-----------FSILEQFVEVFDQQSNICVQRLAQKANGNTFDVYRS 170
            .||:.|...|..::.||.           ..:..:|.:||.|  |:        |.....:|...
  Fly   123 LDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQ--NV--------AKSPVVEVREL 177

  Fly   171 ICAAALDIIAETAMGTKIYAQANESTPYAEAVNECTAL----LSWRFM---SVYLQ----VELLF 224
            :.....|:|...|.|.                 ||::|    ..:|.|   |:..|    |.:.|
  Fly   178 LARFTTDVIGTCAFGI-----------------ECSSLKDPDAEFREMGRRSLTEQRLGPVGIGF 225

  Fly   225 TLTHPHLKWR--QTQLIRTMQEFTIKVIEKRRQALEDQQSKLMDTADEDVGSKRRMALLDVLLMS 287
            ..:.|:|..|  .......::.|.::::.:.....|....:..|..|:.:..|.:.      ||.
  Fly   226 VNSFPNLARRLHMKMTAEPIERFFMRIVRETVAFREQNNIRRNDFMDQLIDLKNKP------LMV 284

  Fly   288 TVDGRP--LTNDEIREEVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRP 350
            :..|..  ||.:||..:...|...|.:|:::.:.|.|:||:::.::|.::.:|..:|:......
  Fly   285 SQSGESVNLTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCNGE- 348

  Fly   351 VSIRDLGELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDGVIPAGSEIIIGIFGVHR- 414
            ::...:.:|.|::.|:.|:||:|..:|::.|:...|::...  |...||..|..::|....:||
  Fly   349 LNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPG--HPKYVIKKGMPVLIPCGAMHRD 411

  Fly   415 -----QPETFPNPDEFIPERHENGSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYEL 474
                 .|.|| |||.|.|||.:....|   :.:||..|||||||.:|.|::.::.||.::::::.
  Fly   412 EKLYANPNTF-NPDNFSPERVKERDSV---EWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKF 472

  Fly   475 -------LPMGQRVECIVNIVLRSETGFQL 497
                   :||....|.   .::.|.:|..|
  Fly   473 SVCEKTTIPMTYNKEM---FLIASNSGIYL 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	107/482 (22%)
Cyp6a21	NP_611003.2	CYP6-like	68..498	CDD:410679	107/483 (22%)