Protein Alignment Cyp4d8 and Cyp4d2

DIOPT Version :9

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001284806.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 507
• Identity: 257/507 - (50%)
• Similarity: 348/507 - (68%)
• Gaps: 20/507 - (3%)

  Fly     1 MLLFLLVVLLFGAGWIIHLGQADRRRKVANLPGPICPPLIGAMQLMLRLNPKTFIKVGREYVLKF 65
            :|:....:||:...|        |||....||||...|.:|.:.:...|:|:..:...::...|:
  Fly     9 LLVAFATLLLWDFLW--------RRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKY 65

  Fly    66 GHLQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNGLLLSDGKVWHQRRKIIT 130
            |.|.||||.::|.:.|.|....|.:||||:|:.|:.:||:|..|||:|||:|.|:.||.||||||
  Fly    66 GRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHGRRKIIT 130

  Fly   131 PTFHFSILEQFVEVFDQQSNICVQRLAQKANGNT-FDVYRSICAAALDIIAETAMGTKIYAQANE 194
            |||||.|||||||:|||||.:.|::|..:|:|.| .:::..||..||||||||||||||.||.|.
  Fly   131 PTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKINAQKNP 195

  Fly   195 STPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQTQLIRTMQEFTIKVIEKRRQALED 259
            :.||.:|||:.|.:|..||:..:.:|:.:|.||.|....||.:.|:.|.:||..:|.:||:.|.:
  Fly   196 NLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVN 260

  Fly   260 QQSKLMDTADEDV---GSKRRMALLDVLLMSTVDGRPLTNDEIREEVDTFMFEGHDTTTSALSFC 321
            ...:  .|.:|:|   |.|||||||||||.||:||.||::::|||||||||||||||||||:|||
  Fly   261 NSKE--TTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTSAISFC 323

  Fly   322 LHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESLRMYPPVPIVGRKLQTD 386
            |:|:|||||||.::.:||..|||.||..||::|||||||:||.|||||||::||||::||....|
  Fly   324 LYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAED 388

  Fly   387 FKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETFPNPDEFIPERHE-NGSRVAPFKMIPFSAGPRN 450
            .:    :.|.. ||||:...:|||.:.|.||.|.:||||.|||.: :..::.|:..|||||||||
  Fly   389 VE----IRGKH-IPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQIHPYAYIPFSAGPRN 448

  Fly   451 CIGQKFAQLEMKMMLAKIVREYELLPMGQRVECIVNIVLRSETGFQLGMRKR 502
            |||||||.||||..::|::|.:||||:|......:||||||..|..||::.|
  Fly   449 CIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHSMNIVLRSANGVHLGLKPR 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	238/435 (55%)
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	246/469 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449003
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28797
OrthoDB	1	1.010	-	-		D10482at33392
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	11	10.910