Protein Alignment Cyp4d8 and cyp26a1

DIOPT Version :9

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_571221.2
• Gene: cyp26a1 / 30381
• ZFINID: ZDB-GENE-990415-44
• Length: 492
• Species: Danio rerio
• Alignment Length: 488
• Identity: 130/488 - (26%)
• Similarity: 211/488 - (43%)
• Gaps: 66/488 - (13%)

  Fly     1 MLLFLLVVLLFGAGW-IIHLGQADRRRKVANLPGPICPPLIGAMQLMLRLNPKTFIKVGREYVLK 64
            :||||..|.|    | ::.:.:.|...:....||.:..|.||. .|.|.|..:.|:::.|:   |
Zfish    18 VLLFLAAVKL----WEMLMIRRVDPNCRSPLPPGTMGLPFIGE-TLQLILQRRKFLRMKRQ---K 74

  Fly    65 FGHLQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQW-------LGNGLLLSDGKVW 122
            :|.:.:..:|....:....|:...|:|..:..||.       .||       ||:..|.:...|.
Zfish    75 YGCIYKTHLFGNPTVRVMGADNVRQILLGEHKLVS-------VQWPASVRTILGSDTLSNVHGVQ 132

  Fly   123 HQ-RRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKANGNTFDVYRSICAAALDIIAETAMGT 186
            |: ::|.|...|....||.::.|..|:....:|...||  .:...||..:......|.....:|.
Zfish   133 HKNKKKAIMRAFSRDALEHYIPVIQQEVKSAIQEWLQK--DSCVLVYPEMKKLMFRIAMRILLGF 195

  Fly   187 KIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQTQLIRTMQEFTIKVIE 251
            :......:.....||..|....|      ..|.:::.|:..:..|:.|  ..|.:      |:.|
Zfish   196 EPEQIKTDEQELVEAFEEMIKNL------FSLPIDVPFSGLYRGLRAR--NFIHS------KIEE 246

  Fly   252 KRRQALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTVDGRPLTNDEIREEVDTFMFEGHDTTTS 316
            ..|:.::|.        |.:...|.:.||..::..|.....|.:...::|.....:|.||:||.|
Zfish   247 NIRKKIQDD--------DNENEQKYKDALQLLIENSRRSDEPFSLQAMKEAATELLFGGHETTAS 303

  Fly   317 ALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRP---VSIRDLGELKYMECVIKESLRMYPPVPI 378
            ..:..:..|..:.||..|:.||:.:.:......|   :|:..|.:|||..|||||:||:.||||.
Zfish   304 TATSLVMFLGLNTEVVQKVREEVQEKVEMGMYTPGKGLSMELLDQLKYTGCVIKETLRINPPVPG 368

  Fly   379 VGRKLQTDFKYTHSVHGDGV-IPAGSEIIIGIFGVHRQPETFPNPDEFIPERH-----ENGSRVA 437
            ..|.....|:.      :|. ||.|..:|..|...|...:.|||.|||.|||.     |:|||
Zfish   369 GFRVALKTFEL------NGYQIPKGWNVIYSICDTHDVADVFPNKDEFQPERFMSKGLEDGSR-- 425

  Fly   438 PFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVR 470
             |..|||..|.|.|:|::||::.:|:.|.::.:
Zfish   426 -FNYIPFGGGSRMCVGKEFAKVLLKIFLVELTQ 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	111/422 (26%)
cyp26a1	NP_571221.2	p450	14..487	CDD:299894	130/488 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2429
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940