Protein Alignment Cyp4d8 and Cyp4f6

DIOPT Version :10

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: XP_006241111.1
• Gene: Cyp4f6 / 266689
• RGDID: 708365
• Length: 538
• Species: Rattus norvegicus
• Alignment Length: 519
• Identity: 169/519 - (32%)
• Similarity: 264/519 - (50%)
• Gaps: 53/519 - (10%)

  Fly     7 VVLLFGAGWIIHLGQA------DRRRKVANLPGPICPPLIGAMQLMLRLNPKTFIKVGREYVLKF 65
            ::||.||.||:....|      |...::...|.|..|........:::.|.:     |.:::...
  Rat    22 LLLLGGASWILARILAWIYTFYDNCCRLRCFPQPPKPSWFWGHLTLMKNNEE-----GMQFIAHL 81

  Fly    66 G------HLQRVWI-----FNRLLIMSGDAELNEQLLSSQEHLVKH-PVYKVLGQWLGNGLLLSD 118
            |      ||.  |:     ..||:..:..|.|   |.:|.....|. .:|..|..|||:|||:|.
  Rat    82 GRNFRDIHLS--WVGPVYPILRLVHPNVIAPL---LQASAAVAPKEMTLYGFLKPWLGDGLLMSA 141

  Fly   119 GKVWHQRRKIITPTFHFSILEQFVEVFDQQSNIC---VQRLAQKANGNTFDVYRSICAAALDIIA 180
            |:.|:..|:::||.|||.||:.:|::|::..|..   .|||..|.:.. .|::..|....||.:.
  Rat   142 GEKWNHHRRLLTPAFHFDILKSYVKIFNKSVNTMHAKWQRLTAKGSAR-LDMFEHISLMTLDSLQ 205

  Fly   181 ETAMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQTQLIRTMQEF 245
            :.........|.:.| .|..|:.|.::|:..|....:|.::.|:.||....::|:.  ...:..|
  Rat   206 KCIFSFDSNCQESNS-EYIAAILELSSLIVKRQRQPFLYLDFLYYLTADGRRFRKA--CDVVHNF 267

  Fly   246 TIKVIEKRRQALEDQQSKLMDTADEDVGSK---RRMALLDVLLMSTVD-GRPLTNDEIREEVDTF 306
            |..||.:||..|..|      ..||.:.::   :.:..:||||::..: |:.|::.:||.|.|||
  Rat   268 TDAVIRERRSTLNTQ------GVDEFLKARAKTKTLDFIDVLLLAKDEHGKGLSDVDIRAEADTF 326

  Fly   307 MFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESLR 371
            ||.|||||.||||:.|:.|:||||.|.:..:|:.::|.......:...||.:|.::...||||||
  Rat   327 MFGGHDTTASALSWILYNLARHPEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCIKESLR 391

  Fly   372 MYPPVPIVGRKLQTDFKYTHSVHGDG-VIPAGSEIIIGIFGVHRQPETFPNPDEFIPERH--ENG 433
            ::|||.::.|....|.     |..|| |||.|:..:|.|||||..|..:|:|:.:.|.|.  ||.
  Rat   392 LHPPVLLISRCCSQDI-----VLPDGRVIPKGNICVISIFGVHHNPSVWPDPEVYNPFRFDPENP 451

  Fly   434 SRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVECIVNIVLRSETGFQL 497
            .:.:|...|||||||||||||.||..|:|:.||..:..:.:||..:.......::||:|.|..|
  Rat   452 QKRSPLAFIPFSAGPRNCIGQTFAMSEIKVALALTLLRFCVLPDDKEPRRKPELILRAEGGLWL 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	155/452 (34%)
Cyp4f6	XP_006241111.1	CYP4F	75..516	CDD:410772	156/461 (34%)