Protein Alignment Cyp4d8 and erg11

DIOPT Version :10

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_592990.1
• Gene: erg11 / 2542599
• PomBaseID: SPAC13A11.02C
• Length: 495
• Species: Schizosaccharomyces pombe
• Alignment Length: 483
• Identity: 103/483 - (21%)
• Similarity: 190/483 - (39%)
• Gaps: 103/483 - (21%)

  Fly    53 TFIKVGREYVLKFGHLQRVWIFNRLLIMSGDAELNEQLLSSQEHLV-----KHPVYKVLGQWLGN 112
            ||:.:||:.....|.....::||..|     |:||.:  .:..||.     |..||.:
pombe    69 TFVCMGRKMTAFLGVQGNDFLFNGKL-----ADLNAE--EAYSHLTTPVFGKDVVYDI------- 119

  Fly   113 GLLLSDGKVWHQRRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKANG--NTFDVYRSICAAA 175
                 ...|:.:.:|.|.....||....:|.:...:.:..:........|  ...|:.:::....
pombe   120 -----PNHVFMEHKKFIKSGLGFSQFRSYVPLILNEMDAFLSTSPDFGPGKEGVADLLKTMPVMT 179

  Fly   176 LDIIAETAMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKW------- 233
            :...:.|..|.::....:..                 |..:|..::..|:..:....|
pombe   180 IYTASRTLQGAEVRKGFDAG-----------------FADLYHDLDQGFSPVNFVFPWLPLPRNR 227

  Fly   234 RQTQLIRTMQEFTIKVIEKRRQALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTV--DGRPLTN 296
            |:.:..:.||:..:|:|:.||.:.|:..:.::.|                 |||..  |||||..
pombe   228 RRDRAHKIMQKTYLKIIKDRRSSTENPGTDMIWT-----------------LMSCKYRDGRPLKE 275

  Fly   297 DEIREEVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPV-SIRDLGELK 360
            .||...:...:..|..|:.:.:.:.|..|...||:...:.||..:|:|.:..... ..:|:..|.
pombe   276 HEIAGMMIALLMAGQHTSAATIVWVLALLGSKPEIIEMLWEEQKRVVGENLELKFDQYKDMPLLN 340

  Fly   361 YMECVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDG-VIPAGSEIIIGIFGVHRQPETFPNPDE 424
            |   ||:|:||::||:....||::.|.    .|.|.. ||||.:.::........:.|.|.:..:
pombe   341 Y---VIQETLRLHPPIHSHMRKVKRDL----PVPGSKIVIPANNYLLAAPGLTATEEEYFTHATD 398

  Fly   425 FIPER-------HENGSRV------------APFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVR 470
            |.|:|       .||..::            :|:  :||.||...|||::||.:.:..:::|.|.
pombe   399 FDPKRWNDRVNEDENAEQIDYGYGLVTKGAASPY--LPFGAGRHRCIGEQFAYMHLSTIISKFVH 461

  Fly   471 EYELLPMGQRVECIVNIVLRSETGFQLG 498
            :|....:|:    :.|:...|.....||
pombe   462 DYTWTLIGK----VPNVDYSSMVALPLG 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	97/467 (21%)
erg11	NP_592990.1	CYP51-like	60..492	CDD:410668	103/483 (21%)