Protein Alignment Cyp4d8 and cyp-25A1

DIOPT Version :9

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 531
• Identity: 128/531 - (24%)
• Similarity: 240/531 - (45%)
• Gaps: 62/531 - (11%)

  Fly     1 MLLFLLVVLLFGAGWIIHLGQADR---RRKVANLPGPICPPLIGAMQLMLRLNPKT--------F 54
            ::|..||:.:|.....|.|.:.:|   |.|: .|.||.....:|.::.......|.        |
 Worm     4 LILSSLVISIFTFFIYIILARRERFKLREKI-GLSGPEPHWFLGNLKQTAERKEKLGYDDANRWF 67

  Fly    55 IKVGREYVLKFGHLQRVWIFNRL-LIMSGDAELNEQLLSSQEHLVKHPVYKV--LGQWLGNGLLL 116
            .::..:|...||    ::..::: :::|.:.::.|..:.:..:.....|..:  ..|...:.|:.
 Worm    68 NELHEQYGETFG----IYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPSIYEANQLTASLLMN 128

  Fly   117 SDGKVWHQRRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKA-NGNTFDVYRSICAAALDIIA 180
            |....|...|..|.|.|....::...|..:.:.::.:..|.:|| :|..:|:|.......||:|.
 Worm   129 SYSSGWKHTRSAIAPIFSTGKMKAMQETINSKVDLFLDILREKASSGQKWDIYDDFQGLTLDVIG 193

  Fly   181 ETAMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLK--WRQTQLIRTMQ 243
            :.|.......|.:.:..:.....:..:.:..|...:.....||     |.|.  |:.......:.
 Worm   194 KCAFAIDSNCQRDRNDVFYVNAKKYISNIDIRHSKIIAASVLL-----PELSTFWKALYKYTPLA 253

  Fly   244 EFTIKVIE------KRRQALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTVD-GRPLTNDEIRE 301
            :..|.::|      :||:..|..     |:.|          ||.:||....| .:|:|..|:.|
 Worm   254 DAEIPLVEGLSNVYERRRGGEGS-----DSVD----------LLKLLLNREDDKSKPMTKQEVIE 303

  Fly   302 EVDTFMFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVI 366
            ....|:..|::||::|:::|.:.||::|.||.|:.|||::   ...:..::...:..:||::||.
 Worm   304 NCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIME---AKENGGLTYDSIHNMKYLDCVY 365

  Fly   367 KESLRMYPPV-PIVGRKLQTDFKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETFPNPDEFIPERH 430
            ||:||.|||| ..:.|..:.|.    ::.|. ..|.|:.::.....|||.||.:.:|:||.|||.
 Worm   366 KETLRFYPPVIHFIRRLCREDI----TIRGQ-FYPKGAIVVCLPHTVHRNPENWDSPEEFHPERF 425

  Fly   431 EN-GSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVECIVN---IVLRS 491
            || ..:.:..|.|||..|||.|:|.:||::|.|..:.|::..:||.......:.|.:   :::|.
 Worm   426 ENWEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELKQFEGEADLIPDCNGVIMRP 490

  Fly   492 ETGFQLGMRKR 502
            ....:|.::.|
 Worm   491 NDPVRLHLKPR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	109/448 (24%)
cyp-25A1	NP_497775.3	p450	37..496	CDD:278495	116/490 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2429
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840