Protein Alignment Cyp4d8 and Cyp4a10

DIOPT Version :10

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_034141.3
• Gene: Cyp4a10 / 13117
• MGIID: 88611
• Length: 509
• Species: Mus musculus
• Alignment Length: 517
• Identity: 153/517 - (29%)
• Similarity: 256/517 - (49%)
• Gaps: 94/517 - (18%)

  Fly    39 LIGAMQLMLRLNPKTFIKVGREYVLK-------------FGHLQRVWIFNRLLIMSGDAELNEQL 90
            |:.|:|..|.          |:::||             |||.:          ..||.||.| :
Mouse    31 LVKAVQFYLH----------RQWLLKAFQQFPSPPFHWFFGHEK----------FKGDQELQE-I 74

  Fly    91 LSSQEHL----------------VKHP----------------VYKVLGQWLGNGLLLSDGKVWH 123
            :|..|:.                |..|                .|::|..|:|.||||.:|:.|.
Mouse    75 VSCIENFPSAFPRWFWGSKAYLTVYDPDYMKVILGRSDPKANGAYRLLAPWIGYGLLLLNGQPWF 139

  Fly   124 QRRKIITPTFHFSILEQFVEVFDQQSNICV---QRLAQKANGNTFDVYRSICAAALDIIAETAMG 185
            |.|:::||.||:.||:.:|:.......:.:   :|||.:  .::.::::.|....||.:.:.|..
Mouse   140 QHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLADQ--DSSIEIFQHISLMTLDTVMKCAFS 202

  Fly   186 TK--IYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTL-THPHLKWRQTQLIRTMQEFTI 247
            .|  :....|..| |.:|:.:...|...|..:::.|.:.::.| ::..|..:..||   ..:.|.
Mouse   203 HKGSVQVDGNYRT-YLQAIGDLNNLFHSRVRNIFHQNDTIYKLSSNGRLAKQACQL---AHDHTD 263

  Fly   248 KVIEKRRQALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTVD-GRPLTNDEIREEVDTFMFEGH 311
            .||:.|:..|:|:...      |.:..|||:..||:||.:.:: |..:::.::|.||||||||||
Mouse   264 GVIKLRKDQLQDEGEL------EKIKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTFMFEGH 322

  Fly   312 DTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESLRMYPPV 376
            |||.|.:|:..:.|:.||:.|.:..||:..:||...|  ::...|.::.|....|||:||:||||
Mouse   323 DTTASGVSWIFYALATHPDHQQRCREEVQSLLGDGSS--ITWDHLDQIPYTTMCIKEALRLYPPV 385

  Fly   377 PIVGRKLQTDFKYTHSVHGDG-VIPAGSEIIIGIFGVHRQPETFPNPDEFIPERHENGSRVAPFK 440
            |.:.|:|.|...:.     || .:|.|.::.:.|:|:|..|:.:|||:.|.|.|....|......
Mouse   386 PGIVRELSTSVTFP-----DGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPRHSHS 445

  Fly   441 MIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVEC-IVNIVLRSETGFQLGMRK 501
            .:|||.|.|||||::||..|:|:::|..:..:||||...||.. :..:||:|:.|..|.::|
Mouse   446 FLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLPDPTRVPMPLARLVLKSKNGIYLHLKK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	143/471 (30%)
Cyp4a10	NP_034141.3	CYP4B-like	71..504	CDD:410771	138/452 (31%)