Protein Alignment Cyp4d8 and Cyp4v3

DIOPT Version :10

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_598730.1
• Gene: Cyp4v3 / 102294
• MGIID: 2142763
• Length: 525
• Species: Mus musculus
• Alignment Length: 526
• Identity: 197/526 - (37%)
• Similarity: 294/526 - (55%)
• Gaps: 46/526 - (8%)

  Fly     8 VLLFGAGWIIHL--------------GQADRRRKVANLPGPI-CPPLIGAMQLMLRLNPKTFIKV 57
            :||:||...:.|              ..|.:.:::.::|... ..||:| ..|.::.|...|.:.
Mouse    13 LLLWGAASAVSLAGATILISIFPMLVSYARKWQQMRSIPSVARAYPLVG-HALYMKPNNAEFFQQ 76

  Fly    58 GREYVLKFGHLQ--RVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNGLLLSDGK 120
            ...|..:|.||.  ::||....|:....||..|.:|:|.:.:.|..:||.|..|||.|||.|.|.
Mouse    77 LIYYTEEFRHLPIIKLWIGPVPLVALYKAENVEVILTSSKQIDKSFLYKFLQPWLGLGLLTSTGS 141

  Fly   121 VWHQRRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKANGNTFDVYRSICAAALDIIAETAMG 185
            .|..|||::||||||:|||.|::|.::|:||.|.:|.:..|...|:.:..|...|||||.|||||
Mouse   142 KWRTRRKMLTPTFHFTILENFLDVMNEQANILVNKLEKHVNQEAFNCFFYITLCALDIICETAMG 206

  Fly   186 TKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVE---LLFTLTHPHLKWRQTQLIRTMQEFTI 247
            ..|.||:|..:.|...|...:.::..|....:|..:   |:|.....|.:.     ::.:..||.
Mouse   207 KNIGAQSNNDSEYVRTVYRMSDMIYRRMKMPWLWFDLWYLVFKEGRDHKRG-----LKCLHTFTN 266

  Fly   248 KVIEKR---RQALEDQQSKLMDTADEDVGSK-RRMALLDVLLMST-VDGRPLTNDEIREEVDTFM 307
            .||.:|   |:|.||...    .....:.|| :|.|.||:||..| .:|..|:.::|||||||||
Mouse   267 NVIAERVKERKAEEDWTG----AGRGPIPSKNKRKAFLDLLLSVTDEEGNRLSQEDIREEVDTFM 327

  Fly   308 FEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESLRM 372
            |||||||.:|:::.|:.|..:||||.|:.:|:.:|.|... |||::.||.:|||::|||||:||:
Mouse   328 FEGHDTTAAAINWSLYLLGTNPEVQRKVDQELDEVFGRSH-RPVTLEDLKKLKYLDCVIKETLRV 391

  Fly   373 YPPVPIVGRKLQTDFKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETFPNPDEFIPERH--ENGSR 435
            :|.||:..|.|..|.:.     |...:..|:|.||..:.:||.|..||:|:||.|||.  ||...
Mouse   392 FPSVPLFARSLSEDCEV-----GGYKVTKGTEAIIIPYALHRDPRYFPDPEEFRPERFFPENSQG 451

  Fly   436 VAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVECIV--NIVLRSETGFQLG 498
            ..|:..:|||||||||||||||.:|.|.:||.|:|::.:....:|.|..:  :::||...|..:.
Mouse   452 RHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILRQFWVESNQKREELGLAGDLILRPNNGIWIK 516

  Fly   499 MRKRKH 504
            : ||:|
Mouse   517 L-KRRH 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	179/444 (40%)
Cyp4v3	NP_598730.1	CYP4V	76..515	CDD:410773	181/453 (40%)