Protein Alignment Cyp4d8 and cyp26c1

DIOPT Version :10

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: XP_031761583.1
• Gene: cyp26c1 / 100489980
• XenbaseID: XB-GENE-1219115
• Length: 608
• Species: Xenopus tropicalis
• Alignment Length: 626
• Identity: 137/626 - (21%)
• Similarity: 222/626 - (35%)
• Gaps: 195/626 - (31%)

  Fly     6 LVVLLFGAGWIIHLGQADRRRKVANLP---GPICPPLIGAMQLMLRLNPKTFIKVGREYVLKFGH 67
            ||:||..:..:..|.....|.:.::||   |.:..|..|. .|...:...:|....||   |:|:
 Frog    22 LVLLLAASHQLWSLRWHSTRDRGSSLPLPKGSMGWPFFGE-TLHWLVQGSSFHSSRRE---KYGN 82

  Fly    68 LQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQW-------LG-NGLLLSDGKVWHQ 124
            :.:..:..:.:|....||...::|..:.|||.       .||       || |.|..|.|::..|
 Frog    83 IFKTHLLGKPVIRVTGAENIRKILLGEHHLVS-------TQWPQSTQIILGSNTLSNSIGELHRQ 140

  Fly   125 RRKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKANGNTFDVYRSI-------CAAALD--IIA 180
            :||:::.....:.||.:           :.|:.:..........|.:       ||.||.  |.|
 Frog   141 KRKMMSKVLSSAALESY-----------LPRIHEAVRWEVRSWCRGVGPVSMLSCAKALTFRIAA 194

  Fly   181 ETAMGTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQTQLIRTMQEF 245
            ...:|..:     ..|.:.|.......|:...|.   |.:::.|:.....:|.|.| |.:.|:|
 Frog   195 RILLGLSL-----TDTQFQELTRTFEQLVENLFC---LPLDIPFSGLRKGMKARDT-LHQYMEE- 249

  Fly   246 TIKVIEKRRQALEDQQSKLMDTADEDVGSKRRMALLDVLLMSTVD-GRPLTNDEIREEVDTFMFE 309
                      |::::.||....|.||.        ||.|:.|..: |:.:...|::|.....:|.
 Frog   250 ----------AIKEKLSKRDPDACEDA--------LDYLINSAKEGGKEINMQELKESAIELIFA 296

  Fly   310 GHDTTTSALSFCLHELSRHP--------------------------------------------- 329
            ...||.||.:..:..|.:||
 Frog   297 AFLTTASASTSLVLLLLKHPSAIHKIRQELASHGLSEHCEQCLPATENPNNNILQDNGHQCLTAG 361

  Fly   330 ---------EVQAKMLEEIVQVLGTDRS------------------------------------- 348
                     |.|.|.|.|..:.|.|||:
 Frog   362 CQLPLVMGTEGQVKTLWEQTKQLLTDRTDQDPQNSLSSKNLVNGENRIQEAPCSHDKSNCSPVPG 426

  Fly   349 ------------RPVSIRDLGELKYMECVIKESLRMYPPVPIVGRKLQTDFKYTHSVHGDGV-IP 400
                        :.:|:..|..|.|::||:||.||:.|||....|.....|:.      ||. ||
 Frog   427 KLQNSVFEGTCQQNISLEKLKSLHYLDCVVKEVLRLLPPVSGGYRTALQTFEL------DGYQIP 485

  Fly   401 AGSEIIIGIFGVHRQPETFPNPDEFIPER---HENGSRVAPFKMIPFSAGPRNCIGQKFAQLEMK 462
            .|..::..|...|.....:.|.:.|.|||   ..:..::..|..|||..|.|:|||::.||:.:|
 Frog   486 KGWSVMYSIRDTHETAAVYQNAEMFDPERFSTERDEGKLGRFNYIPFGGGARSCIGKELAQIILK 550

  Fly   463 MMLAKIV--REYEL----LPMGQRVECIVNIVLRSETGFQL 497
            ::..::|  .::||    .|..|.|.     |:....|.||
 Frog   551 ILAMELVTTAKWELATPSFPKMQTVP-----VVHPVDGLQL 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	119/561 (21%)
cyp26c1	XP_031761583.1	cytochrome_P450	59..588	CDD:477761	127/589 (22%)