Protein Alignment Cyp4d8 and cyp4v2

DIOPT Version :10

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: XP_002934446.1
• Gene: cyp4v2 / 100485929
• XenbaseID: XB-GENE-22069503
• Length: 523
• Species: Xenopus tropicalis
• Alignment Length: 518
• Identity: 200/518 - (38%)
• Similarity: 305/518 - (58%)
• Gaps: 32/518 - (6%)

  Fly     1 MLLFLLVVLLFGAGWIIHLGQADRRRKVAN-LPGPICP--PLIGAMQLMLRLNPKTFIKVGREYV 62
            :||.||.:.:..|     |....|:.|:.. :||| .|  |::|. .|.|:.|...|.....|:.
 Frog    18 VLLTLLALSILPA-----LQDYVRKWKLMKPIPGP-GPNYPIVGD-ALFLKPNGGDFFLQMCEFT 75

  Fly    63 LKFGH--LQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNGLLLSDGKVWHQR 125
            ..|..  |.::||.....|:...|:..|.:||:.:|:.|...||.|..|||.|||.|.|:.|..|
 Frog    76 ESFRSEPLIKIWIGPIPFIIVYHADTVEPILSTSKHMDKAYSYKFLHPWLGKGLLTSTGEKWRSR 140

  Fly   126 RKIITPTFHFSILEQFVEVFDQQSNICVQRLAQKANGNTFDVYRSICAAALDIIAETAMGTKIYA 190
            ||:|||||||:||.:|:||.::||.|.|::|.:..:|.:|:.:..:...|||||:|||||.||.|
 Frog   141 RKMITPTFHFAILSEFLEVMNEQSKILVEKLQKHVDGESFNCFMDVTLCALDIISETAMGRKIQA 205

  Fly   191 QANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLK--WRQTQLIRTMQEFTIKVIEKR 253
            |:|..:.|..|:.:.:.::..|....:|.::..:.    :||  ....:.::.:..||.|.|.:|
 Frog   206 QSNRDSEYVHAIYKMSDIIQRRQKMPWLWLDFFYA----YLKDGKEHDKNLKILHAFTDKAILER 266

  Fly   254 RQALE---DQQSKLMDTADEDVGSKRRMALLDVLLMSTVD-GRPLTNDEIREEVDTFMFEGHDTT 314
            .:.|:   :|:.:..|:..|....|:|.|.||:|||:|.| |..::..:||||||||||||||||
 Frog   267 AEELKKMGEQKKEHCDSDPESDKPKKRSAFLDMLLMATDDAGNKMSYMDIREEVDTFMFEGHDTT 331

  Fly   315 TSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESLRMYPPVPIV 379
            .:||::.|..|..|||.|.::.:|:.:|.|.. .|||::.||.:|:|:|.||||:||:||.||..
 Frog   332 AAALNWSLFLLGSHPEAQRQVHKELDEVFGKS-DRPVTMDDLKKLRYLEAVIKEALRIYPSVPFF 395

  Fly   380 GRKLQTDFKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETFPNPDEFIPERH--ENGSRVAPFKMI 442
            .|.:..|.    |:.|..| |.|..::|..:.:||.||.||.|:||.|||.  ||.|...|:..|
 Frog   396 ARTVTEDC----SIRGFHV-PKGVNVVIIPYALHRDPEYFPEPEEFRPERFFPENASGRNPYAYI 455

  Fly   443 PFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPMGQRVE-CIV-NIVLRSETGFQLGMRKRK 503
            |||||.||||||:||.:|.|::|:.|:|.|.:....:|.: |:: :::||.:.|..:.::.|:
 Frog   456 PFSAGLRNCIGQRFALMEEKVVLSSILRNYWVEASQKREDLCLLGDLILRPQDGMWIKLKNRE 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	179/442 (40%)
cyp4v2	XP_002934446.1	CYP4V	70..512	CDD:410773	181/451 (40%)