Protein Alignment Cyp4d8 and Cyp2c69

DIOPT Version :9

• Sequence 1: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001097995.1
• Gene: Cyp2c69 / 100043108
• MGIID: 3721049
• Length: 491
• Species: Mus musculus
• Alignment Length: 500
• Identity: 114/500 - (22%)
• Similarity: 209/500 - (41%)
• Gaps: 72/500 - (14%)

  Fly     7 VVLLFGAGWIIHLGQADRRRKVANL-PGPICPPLIGAMQLM--------LRLNPKTFIKVGREYV 62
            |||:....:::.|....:|....|| |||...|:||...|:        |....||:   |..:.
Mouse     5 VVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTY---GPVFT 66

  Fly    63 LKFGHLQRVWIFNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQW-------LGNGLLLSDGK 120
            |.||.       ..::::.|...:.|.|:...|      |:...|.:       .|.|:..|.|.
Mouse    67 LYFGS-------QPIVVLHGYEAIKEALIDHGE------VFSGRGSFPFFDKVSKGKGIGFSHGN 118

  Fly   121 VWHQRRKIITPTF-HFSILEQFVEVFDQQSNICVQRLAQKANGNTFDVYRSICAAALDIIAETAM 184
            ||...|.....|. :.::.::.:|...|:....:.:..:|.||:..|....|..|..::|.....
Mouse   119 VWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVF 183

  Fly   185 GTKIYAQANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQTQLIRT---MQEFT 246
            ..:...:..:.......|||||.:||.....::..|.:|.    .:...|..:..:.   ::.:.
Mouse   184 QNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILI----DYCPGRHNKFFKNHTWIKSYL 244

  Fly   247 IKVIEKRRQALEDQQSKLMDTADEDVGSKRRMALLDVLLMST-----VDGRPLTNDEIREEVDTF 306
            ::.|::..::|             ||.:.|  ..:|..|:..     ::....|.:.:...|...
Mouse   245 LEKIKEHEESL-------------DVTNPR--DFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDL 294

  Fly   307 MFEGHDTTTSALSFCLHELSRHPEVQAKMLEEIVQVLGTDRSRPVSIRDLGELKYMECVIKESLR 371
            :|.|.:|.:|.:.|.|..|.:|..:.||:.|||..|:|  |.|...::|...:.|...::.|..|
Mouse   295 VFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIG--RHRSPCMQDRKHMPYTNAMVHEVQR 357

  Fly   372 MYP--PVPIVGRKLQTDFKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETFPNPDEFIPER--HEN 432
            ...  |..:| .::..|.|:.:.     .||.|::::..:..|......||||:.|.|..  .:|
Mouse   358 YVDLGPTSLV-HEVTCDTKFRNY-----FIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDN 416

  Fly   433 GSRVAPFKMIPFSAGPRNCIGQKFAQLEMKMMLAKIVREYELLPM 477
            |:.......:|||||.|.|:|:..|::|:.:.|..|::.::|.|:
Mouse   417 GNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPL 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	94/431 (22%)
Cyp2c69	NP_001097995.1	p450	30..487	CDD:278495	107/474 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010